CAJ | 학술논문

目的：探讨麻醉前应用右美托咪啶对瑞芬太尼与丙泊酚静脉复合全身麻醉患者苏醒期的影响。方法随机选择广西医科大学附属医院贵港市人民医院2011年5月至2013年5月120例采用瑞芬太尼与丙泊酚静脉复合全身麻醉的患者为研究对象，其中观察组60例麻醉前应用右美托咪啶，对照组60例麻醉前未应用右美托咪啶。观察清醒时间、拔管时间以及术后拔管情况。结果观察组镇静效果评分为（2.3±1.2）分，不良反应发生率为2.8%，与对照组比较差异有统计学意义（ P﹤0.05）。结论麻醉前应用右美托咪啶可以缩短全身麻醉患者的苏醒时间，降低相关不良反应发生率，从而成为理想的麻醉前用药。
목적：탐토마취전응용우미탁미정대서분태니여병박분정맥복합전신마취환자소성기적영향。방법수궤선택엄서의과대학부속의원귀항시인민의원2011년5월지2013년5월120례채용서분태니여병박분정맥복합전신마취적환자위연구대상，기중관찰조60례마취전응용우미탁미정，대조조60례마취전미응용우미탁미정。관찰청성시간、발관시간이급술후발관정황。결과관찰조진정효과평분위（2.3±1.2）분，불량반응발생솔위2.8%，여대조조비교차이유통계학의의（ P﹤0.05）。결론마취전응용우미탁미정가이축단전신마취환자적소성시간，강저상관불량반응발생솔，종이성위이상적마취전용약。
Objective To investtigate the effect of dexmedetomidine used before anesthesia on awakening period of patients with intravenous combined general anesthesia with remifentanil and propofol. Methods From May 2011 to May 2013,120 pa-tients with intravenous combined general anesthesia with remifentanil and propofol were selected. The 60 patients in observation group were given dexmedetomidine before anesthesia,and 60 patients in control group were not given dexmedetomidine before an-esthesia. The awaking time,extubation time and postoperative extubation was observed. Results In observation group,the sed-ative effect score was(2. 3 ± 1. 2),and the incidence of adverse reactions was 2. 8%,compared with the control group,there were significant differences. Conclusion Dexmedetomidine used before anesthesia can shorten the awaking time,reduce the in-cidence of adverse reactions,so is the ideal preanesthetic medication.