CAJ | 학술논문

目的：观察无创双水平气道正压通气（ BiPAP）辅助治疗慢性阻塞性肺疾病（ COPD）合并Ⅱ型呼吸衰竭的疗效。方法将我院RICU的84例COPD合并Ⅱ型呼吸衰竭患者，随机分为无创通气组和常规治疗组。两组均予常规药物治疗。无创组辅以BiPAP无创通气，常规组予鼻导管吸氧，观察治疗2 h前后动脉血气的变化及无创通气对患者插管率的影响。结果相对于常规治疗组，BiPAP无创通气2 h可有效纠正呼吸性酸中毒，降低 PCO2，提高 PO2，降低插管率（P均﹤0.05）。结论 BiPAP无创通气可缓解COPD合并Ⅱ型呼吸衰竭患者呼吸困难，改善血气，降低气管插管率。
목적：관찰무창쌍수평기도정압통기（ BiPAP）보조치료만성조새성폐질병（ COPD）합병Ⅱ형호흡쇠갈적료효。방법장아원RICU적84례COPD합병Ⅱ형호흡쇠갈환자，수궤분위무창통기조화상규치료조。량조균여상규약물치료。무창조보이BiPAP무창통기，상규조여비도관흡양，관찰치료2 h전후동맥혈기적변화급무창통기대환자삽관솔적영향。결과상대우상규치료조，BiPAP무창통기2 h가유효규정호흡성산중독，강저 PCO2，제고 PO2，강저삽관솔（P균﹤0.05）。결론 BiPAP무창통기가완해COPD합병Ⅱ형호흡쇠갈환자호흡곤난，개선혈기，강저기관삽관솔。
Objective To observe the therapeutic effects of noninvasive bi-level positive airway pressure( BiPAP)ventila-tion on chronic obstructive pulmonary disease( COPD)complicated with typeⅡ respiratory failure patients. Methods Eighty-four cases of COPD complicated with type Ⅱrespiratory failure in our hospital RICU were randomly divided into the noninvasive group and the conventional group. Besides routine drug therapy,43 cases in the noninvasive group were administered with BiPAP ventilation,other 41 cases in the conventional group were administered with oxygen inhalation through nasal catheter. The chan-ges of arterial blood gas,reintubation rate were observed in the two groups. Results Compared with the conventional group,the noninvasive group had better blood gas improvement and lower reintubation rate after 2 hours of noninvasive ventilation( P ﹤0. 05). Conclusion The noninvasive BiPAP ventilation can relieve the syndrome of dyspnea,improve blood gas and lower rein-tubation rate for COPD complicated with typeⅡ respiratory failure cases.