CAJ | 학술논문

目的：探讨伽玛刀与手术治疗颞叶癫痫的疗效，寻求更佳的颞叶癫痫治疗方法。方法回顾性分析我院接受伽玛刀治疗颞叶癫痫患者35例，治疗边缘剂量15～25 Gy，接受手术治疗颞叶癫痫患者102例，随访患者治疗后癫痫控制情况。结果随访时间3～7年，平均4．5年，伽玛刀治疗组EngelⅠ级7例， EngelⅡ级8例， EngelⅢ级9例，EngelⅣ级11例，手术治疗组：EngelⅠ级69例，EngelⅡ级15例，EngelⅢ级10例，EngelⅣ级8例，两者差异有显著统计学意义（P＜0．0001）。结论手术治疗颞叶癫痫疗效显著优于伽玛刀治疗，伽玛刀术后癫痫缓解率低，并发症多，目前尚不能作为颞叶癫痫的常规治疗。
목적：탐토가마도여수술치료섭협전간적료효，심구경가적섭협전간치료방법。방법회고성분석아원접수가마도치료섭협전간환자35례，치료변연제량15～25 Gy，접수수술치료섭협전간환자102례，수방환자치료후전간공제정황。결과수방시간3～7년，평균4．5년，가마도치료조EngelⅠ급7례， EngelⅡ급8례， EngelⅢ급9례，EngelⅣ급11례，수술치료조：EngelⅠ급69례，EngelⅡ급15례，EngelⅢ급10례，EngelⅣ급8례，량자차이유현저통계학의의（P＜0．0001）。결론수술치료섭협전간료효현저우우가마도치료，가마도술후전간완해솔저，병발증다，목전상불능작위섭협전간적상규치료。
Objective To explore the efficacy of gamma knife and surgery treatment for temporal lobe epilepsy in order to seek for better treatment of temporal lobe epilepsy .Methods The clinical data of 35 patients with temporal lobe epilepsy treated by gamma knife in our department were analyzed retrospectively .The marginal dose ranged from 15-25 Gy.In the same period , 102 patients with temporal lobe epilepsy were underwent operation , and accepted the follow up after operation . Results The follow-up period ranged from 3 to 7(mean 4.5) years,Engel's criteria were used to classify seizure outcome ,in the gamma knife treatment group ,seizure control of EngelⅠin 7 cases,EngelⅡin 8,EngelⅢin 9 and EngelⅣin11.While the surgical treatment groups showed EngelⅠin 69 cases, EngelⅡin15,EngelⅢin 10 and Engel Ⅳin 8.There was statistically significant difference between gamma knife and surgery treatment group for temporal lobe epilepsy (P <0.0001).Conclusion Surgery treatment for temporal lobe epilepsy is significantly superior efficacy than gamma knife , gamma knife treatment is not yet as a routine treatment for temporal lobe epilepsy .