CAJ | 학술논문

目的：探讨高血糖对全瓷冠固定修复后龈沟液成分的影响。方法：选取近两年在我院口腔修复科就诊的40-50岁，需进行全瓷单冠修复的患者80例为受试对象，其中男性40例，女性40例，常规牙周洁治后采用全瓷单冠修复，分别在修复前以及修复后2个月检测基牙龈沟液的分泌量以及碱性磷酸酶，白细胞介素1β和肿瘤坏死因子α水平。结果：正常血糖患者全瓷修复后2个月基牙龈沟液分泌量，碱性磷酸酶，白细胞介素1和肿瘤坏死因子α水平均无明显升高。高糖组修复后2个月基牙龈沟液分泌量，白细胞介素1和肿瘤坏死因子α显著高于修复前，但碱性磷酸酶水平与修复前比较差异无统计学意义。结论：高糖环境可使全瓷冠修复后患者龈沟液分泌量增加，相关炎性因子表达增高。
목적：탐토고혈당대전자관고정수복후간구액성분적영향。방법：선취근량년재아원구강수복과취진적40-50세，수진행전자단관수복적환자80례위수시대상，기중남성40례，녀성40례，상규아주길치후채용전자단관수복，분별재수복전이급수복후2개월검측기아간구액적분비량이급감성린산매，백세포개소1β화종류배사인자α수평。결과：정상혈당환자전자수복후2개월기아간구액분비량，감성린산매，백세포개소1화종류배사인자α수평균무명현승고。고당조수복후2개월기아간구액분비량，백세포개소1화종류배사인자α현저고우수복전，단감성린산매수평여수복전비교차이무통계학의의。결론：고당배경가사전자관수복후환자간구액분비량증가，상관염성인자표체증고。
Objective:To investigate the effect of hyperglycemia on gingival crevicular fluid after restoration of ceramic crown.Method:80 patients (40 male and 40 female) were randomly selected from the 40 to 50-year-old patients treated in our department in the past two years who were indicated for single ceramic crown. All the patients were treated with routine periodontal prophylaxis and restoration of all-ceramic crowns. The gross secretory volume of gingival crevicular fluid, ALP, IL-1 and TNF-αwere measured before and 2 months after restoration.Results:Among patients with normal blood glucose, there were no significant changes on gross secretory volume of gingival crevicular fluid, ALP, IL-1 and TNF-αlevels 2 months after restoration of all-ceramic crowns. Among patients with hyperglycemia, gross secretory volume of gingival crevicular fluid, IL-1 and TNF-αlevels significantly increased 2 months after restoration of all-ceramic crowns, but level of ALP did not change significantly.Conclusion:Hyperglycemia could promote gingival crevicular fluid secretion, and IL-1, TNF-αlevels in gingival crevicular fluid after restoration of ceramic crown.