CAJ | 학술논문

目的：观察氧化亚氮/氧气混合气体吸入联合氯诺昔康用于烧伤后创面疼痛的临床疗效。方法将48例烧伤后创面疼痛的患者按治疗方法的不同分为2组：观察组（23例）和对照组（25例）。2组均采用注射用氯诺昔康8 mg加入0.9%氯化钠注射液100 mL中静脉滴注，2次·d-1。在此基础上，观察组采用Digital MDM氧化亚氮/氧气混合输出系统治疗。观察2组临床疗效的情况，并对2组进行目测类比疼痛评分（VAS评分）和疼痛问卷评分（疼痛感觉评分和疼痛情绪评分）。结果观察组总有效率明显高于对照组（91.3%比76.0%，P＜0.05）；与对照组比较，观察组治疗1 d后VAS、疼痛感觉和疼痛情绪得分均明显降低（均P＜0.05）。结论氧化亚氮/氧气混合气体吸入联合氯诺昔康用于烧伤后创面疼痛有较好的镇痛效果，且无明显的不良反应。
목적：관찰양화아담/양기혼합기체흡입연합록낙석강용우소상후창면동통적림상료효。방법장48례소상후창면동통적환자안치료방법적불동분위2조：관찰조（23례）화대조조（25례）。2조균채용주사용록낙석강8 mg가입0.9%록화납주사액100 mL중정맥적주，2차·d-1。재차기출상，관찰조채용Digital MDM양화아담/양기혼합수출계통치료。관찰2조림상료효적정황，병대2조진행목측류비동통평분（VAS평분）화동통문권평분（동통감각평분화동통정서평분）。결과관찰조총유효솔명현고우대조조（91.3%비76.0%，P＜0.05）；여대조조비교，관찰조치료1 d후VAS、동통감각화동통정서득분균명현강저（균P＜0.05）。결론양화아담/양기혼합기체흡입연합록낙석강용우소상후창면동통유교호적진통효과，차무명현적불량반응。
Objective To observe the clinical effect of inhalation of nitrous oxide/oxygen mixture combined with lornoxicam on wound pain after burn injury. Methods Forty-eight patients with burn injury pain were divided into observation group(n=23) and control group(n=25). All patients were given 8 mg lornoxicam dissolved in 100 mL 0.9% sodium chloride injection via intravenous drip twice per day. In addition, patients in observation group were treated with the Digital MDM nitrous oxide/oxygen mixer . Clinical effects were observed and visual analogue scale ( VAS ) scores and pain questionnaire scores ( feeling and emotional pain scores ) were determined in both groups . Results Compared with control group,the inhalation of nitrous oxide/oxygen mixture combined with intravenous lornoxicam administration significantly increased the overall response rate ( 91 . 3% vs 76 . 0%, P<0 . 05 ) , and obviously decreased VAS , feeling pain and emotional scores after treatment for 1 day ( P<0 . 05 ) . Conclusion The inhalation of nitrous oxide/oxygen mixture combined with intravenous lornoxicam administration is effective for analgesia and does not cause obvious adverse reactions in patients with wound pain after burn injury.