CAJ | 학술논문

目的：探讨代谢综合征（MS）对老年高血压患者冠状动脉（冠脉）病变的影响。 　　方法：选取2012-06至2013-01入住山西医科大学第一医院行冠脉造影的老年高血压患者210例，根据有无合并MS分为MS组（85例）与非MS组（125例），进而比较两组患者冠脉病变血管分布、支数及Gensini积分的差异，分析MS对老年高血压患者冠脉病变的影响。 　　结果：一般资料比较，MS组体质指数、甘油三酯、高密度脂蛋白胆固醇、空腹血糖水平均明显高于非MS组（P<0.001）；两组患者左主干及左前降支病变分布、冠脉正常者所占比例比较差异无统计学意义（P>0.05）；MS组患者Gensini积分、左回旋支及右冠脉病变分布及冠脉病变者所占比例均高于非MS组,其中冠脉病变患者中以三支病变所占比例差异最为显著（P<0.05）；Logistic回归分析显示MS是冠脉病变的独立危险因素，且高于其单一组分。 　　结论：MS与老年高血压患者冠脉病变的严重程度相关，且影响程度高于单一高血压。
목적：탐토대사종합정（MS）대노년고혈압환자관상동맥（관맥）병변적영향。 　　방법：선취2012-06지2013-01입주산서의과대학제일의원행관맥조영적노년고혈압환자210례，근거유무합병MS분위MS조（85례）여비MS조（125례），진이비교량조환자관맥병변혈관분포、지수급Gensini적분적차이，분석MS대노년고혈압환자관맥병변적영향。 　　결과：일반자료비교，MS조체질지수、감유삼지、고밀도지단백담고순、공복혈당수평균명현고우비MS조（P<0.001）；량조환자좌주간급좌전강지병변분포、관맥정상자소점비례비교차이무통계학의의（P>0.05）；MS조환자Gensini적분、좌회선지급우관맥병변분포급관맥병변자소점비례균고우비MS조,기중관맥병변환자중이삼지병변소점비례차이최위현저（P<0.05）；Logistic회귀분석현시MS시관맥병변적독립위험인소，차고우기단일조분。 　　결론：MS여노년고혈압환자관맥병변적엄중정도상관，차영향정도고우단일고혈압。
Objective: To evaluate the influence of metabolic syndrome (MS) on coronary lesions in elder patients with hypertension. Methods: A cohort of 210 hypertensive patients at the age of 60 years or elder who received coronary angiography in our hospital from 2012-06 to 2013-01 were studied. The patients were divided into 2 groups, MS group,n=85 and Non-MS group,n=125 patients without MS. The coronary lesion distribution, number and Gensini score were analyzed and compared between 2 groups. Results: Compared with Non-MS group, MS group showed increased BMI, TG, HDL-C and fasting blood glucose, allP<0.001. There were no real differences for lesion distribution in left main, left anterior descending branch and the number of patients with normal coronary artery between 2 groups, allP>0.05. MS group had higher Gensini score, more lesions at left circumlfex and right coronary artery, more patients with coronary lesions and more patients with 3-branch disease,P<0.05. Logistic regression analysis indicated that MS is the independent risk factor for coronary lesions and the risk is higher than any single components of MS. Conclusion: MS is related to the severity of coronary lesions in elder patients with hypertension.