中国临床新医学
中國臨床新醫學
중국림상신의학
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
2014年
7期
638-640
,共3页
预防%剖宫产%产后出血%卡前列素氨丁三醇%益母草注射液%联合应用
預防%剖宮產%產後齣血%卡前列素氨丁三醇%益母草註射液%聯閤應用
예방%부궁산%산후출혈%잡전렬소안정삼순%익모초주사액%연합응용
Prevention%Cesarean section%Postpartum hemorrhage%Carboprost tromethamine injec-tion%Motherwort injection%Combined application
目的：观察卡前列素氨丁三醇联合益母草注射液宫体注射预防剖宫产产后出血的疗效。方法选择2012-01～2014-01在该院住院有出血倾向行剖宫产的产妇80例，随机分为实验组和对照组，每组40例。实验组行剖宫产胎儿娩出后即给产妇宫体注射卡前列素氨丁三醇0.25 mg和益母草注射液（20 mg）2 ml；对照组行剖宫产胎儿娩出后予宫体注射缩宫素20 U。观察两组产妇剖宫产产后出血的发生率和产后2 h、24 h的出血量以及用药前后的血压变化情况，并进行比较。结果实验组产后出血发生3例，发生率为7.5％；2h、24 h的出血量分别平均为（356±30.5）ml和（420±26.1）ml。对照组产后出血发生8例，发生率为20.0％；2 h、24 h的出血量分别平均为（425±28.1） ml和（550±27.5） ml。两组比较差异有统计学意义（ P＜0.01）。实验组用药前平均血压为（118±6.3）/（71±5.1）mmHg，用药后平均为（130±8.6）/（80±7.8）mmHg；对照组用药前平均血压为（121±7.7）/（75±6.8）mmHg，用药后平均为（124±6.3）/（77±5.9）mmHg。两组比较差异无统计学意义（P＞0.05）；各组组内用药前后比较，差异亦无统计学意义（P＞0.05）。结论卡前列素氨丁三醇联合益母草注射液预防剖宫产子宫收缩乏力所致的产后出血有较好的临床效果，副作用小，早期使用对产后出血的预防及治疗效果有重要意义。
目的：觀察卡前列素氨丁三醇聯閤益母草註射液宮體註射預防剖宮產產後齣血的療效。方法選擇2012-01～2014-01在該院住院有齣血傾嚮行剖宮產的產婦80例，隨機分為實驗組和對照組，每組40例。實驗組行剖宮產胎兒娩齣後即給產婦宮體註射卡前列素氨丁三醇0.25 mg和益母草註射液（20 mg）2 ml；對照組行剖宮產胎兒娩齣後予宮體註射縮宮素20 U。觀察兩組產婦剖宮產產後齣血的髮生率和產後2 h、24 h的齣血量以及用藥前後的血壓變化情況，併進行比較。結果實驗組產後齣血髮生3例，髮生率為7.5％；2h、24 h的齣血量分彆平均為（356±30.5）ml和（420±26.1）ml。對照組產後齣血髮生8例，髮生率為20.0％；2 h、24 h的齣血量分彆平均為（425±28.1） ml和（550±27.5） ml。兩組比較差異有統計學意義（ P＜0.01）。實驗組用藥前平均血壓為（118±6.3）/（71±5.1）mmHg，用藥後平均為（130±8.6）/（80±7.8）mmHg；對照組用藥前平均血壓為（121±7.7）/（75±6.8）mmHg，用藥後平均為（124±6.3）/（77±5.9）mmHg。兩組比較差異無統計學意義（P＞0.05）；各組組內用藥前後比較，差異亦無統計學意義（P＞0.05）。結論卡前列素氨丁三醇聯閤益母草註射液預防剖宮產子宮收縮乏力所緻的產後齣血有較好的臨床效果，副作用小，早期使用對產後齣血的預防及治療效果有重要意義。
목적：관찰잡전렬소안정삼순연합익모초주사액궁체주사예방부궁산산후출혈적료효。방법선택2012-01～2014-01재해원주원유출혈경향행부궁산적산부80례，수궤분위실험조화대조조，매조40례。실험조행부궁산태인면출후즉급산부궁체주사잡전렬소안정삼순0.25 mg화익모초주사액（20 mg）2 ml；대조조행부궁산태인면출후여궁체주사축궁소20 U。관찰량조산부부궁산산후출혈적발생솔화산후2 h、24 h적출혈량이급용약전후적혈압변화정황，병진행비교。결과실험조산후출혈발생3례，발생솔위7.5％；2h、24 h적출혈량분별평균위（356±30.5）ml화（420±26.1）ml。대조조산후출혈발생8례，발생솔위20.0％；2 h、24 h적출혈량분별평균위（425±28.1） ml화（550±27.5） ml。량조비교차이유통계학의의（ P＜0.01）。실험조용약전평균혈압위（118±6.3）/（71±5.1）mmHg，용약후평균위（130±8.6）/（80±7.8）mmHg；대조조용약전평균혈압위（121±7.7）/（75±6.8）mmHg，용약후평균위（124±6.3）/（77±5.9）mmHg。량조비교차이무통계학의의（P＞0.05）；각조조내용약전후비교，차이역무통계학의의（P＞0.05）。결론잡전렬소안정삼순연합익모초주사액예방부궁산자궁수축핍력소치적산후출혈유교호적림상효과，부작용소，조기사용대산후출혈적예방급치료효과유중요의의。
Objective To observe the effect of uterine body injection of carboprost tromethamine injection combined with motherwort injection for prevention of postpartum hemorrhage of cesarean section .Methods From Jan 2012 to Jan 2014 80 parturients with bleeding tendency for cesarean section were randomly divided into experimental group and control group with 40 cases in each group.After delivery of fetus during cesarean section the experimental group received the uterine body injection of carboprost tromethamine injection 0.25 mg and motherwort injection (20 mg) 2 ml;and the control group received the uterine body injection of 20 U oxytocin .The postpartum hemorrhage rate and post-partum hemorrhage amount at 2 h and 24 h of postpartum , blood pressure changes before and after medication were compared between two groups .Results In the experimental group ,postpartum hemorrhage was found in 3 cases,the incidence rate was 7.5%;the bleeding volume at 2 h and 24 h was (356 ±30.5)ml and (420 ±26.1)ml respective-ly.In the control group , postpartum hemorrhage in 8 cases,the incidence rate was 20.0%;the bleeding volume at 2 h and 24 h was (425 ±28.1)ml and (550 ±27.5)ml respectively.There was significant difference between two groups (P<0.01).In the experimental group,the average blood pressure before treatment was (118 ±6.3)/(71 ±5.1) mmHg,the average blood pressure after treatment was (130 ±8.6)/(80 ±7.8)mmHg.In the control group,the aver-age blood pressure before treatment was (121 ±7.7)/(75 ±6.8)mmHg,that after treatment was (124 ±6.3)/(77 ± 5.9 ) mmHg.There was no significant differences between the two groups ( P>0.05 ) .In comparison within the groups before and after treatment , there were no significant differences in the changes of blood pressure ( P>0.05 ) .Conclu-sion Carboprost tromethamine injection combined with motherwort injection in the prevention of cesarean section ′s postpartum hemorrhage caused by uterine atony have a very good clinical effects ,and the side effect is small ,early use has important significance for the prevention and treatment of postpartum hemorrhage .
