CAJ | 학술논문

采用固相萃取-高效液相色谱/串联质谱法(SPE-HPLC-MS/MS)分析上海市黄浦江流域7种典型药物和个人护理品(PPCPs)的含量水平.结果表明，所建立的分析方法具备良好的回收率(87%~107%)、相对标准偏差(<14%)及方法定量限(0.1~1.1ng/L)，满足水体中微量污染物的检测要求.应用该方法检测得到，上海市黄浦江流域水体中目标 PPCPs的含量在<LOQ~824ng/L范围内，总体浓度水平较低，符合我国药物消费特点.从污染物的空间分布特征看，下游污染比上游严重，支流污染程度大于干流.
채용고상췌취-고효액상색보/천련질보법(SPE-HPLC-MS/MS)분석상해시황포강류역7충전형약물화개인호리품(PPCPs)적함량수평.결과표명，소건립적분석방법구비량호적회수솔(87%~107%)、상대표준편차(<14%)급방법정량한(0.1~1.1ng/L)，만족수체중미량오염물적검측요구.응용해방법검측득도，상해시황포강류역수체중목표 PPCPs적함량재<LOQ~824ng/L범위내，총체농도수평교저，부합아국약물소비특점.종오염물적공간분포특정간，하유오염비상유엄중，지류오염정도대우간류.
The concentrations of 7selected pharmaceuticals and personal care products (PPCPs) in the Huangpu River were determined by solid phase extraction and high liquid chromatography-electrospray tandem mass spectrometry (SPE-HPLC-MS/MS). The results showed that the developed analytical method obtained good recoveries (87~107%), relative standard deviation (<14%) and limit of quantification (0.1~1.1ng/L), satisfying the requirement to detect micropollutants in the surface water. By applying the method in Huangpu River, we found that compared to other reported studies, the contamination levels of target PPCPs were low in Huangpu River, with the concentrations varying from <LOQ to 824ng/L, which were consistent with their consumptions in China. Higher total concentrations were observed in downstream and tributaries sampling sites than in upstream and stream sites.