中国实验诊断学
中國實驗診斷學
중국실험진단학
CHINESE JOURNAL OF LABORATORY DIAGNOSIS
2014年
7期
1105-1107
,共3页
结核杆菌%脂阿拉伯甘露糖%抗体%结核病
結覈桿菌%脂阿拉伯甘露糖%抗體%結覈病
결핵간균%지아랍백감로당%항체%결핵병
Mycobacterium tuberculosis%fat Arabia mannose%antibody%tuberculosis
目的:探讨血清结核杆菌抗体检测在住院患者结核病诊断中的临床价值。方法150例结核病患者,80例非结核病患者以及40例健康志愿者均应用以脂阿拉伯甘露糖(LAM)为抗原的 ELISA法进行抗体阳性率的检测。并应用痰涂片和PPD实验检查对150例结核患者进行检测。结果在150例肺结核患者中,结核杆菌抗体检测的阳性检出率为72.67%(109/150),显著高于痰涂片的51.33%(77/150)和PPD实验的58.67%(88/150),且差异均具有统计学意义(χ2=14.49,6.52;P<0.001,0.011)。结核病组抗体阳性率总数为72.67%(109/150),显著高于非结核病组的17.50%(14/80)和健康对照组的10.00%(4/40),且与二者比较,差异均具有统计学意义(χ2=41.15,51.45;P<0.001,0.001)。非结核疾病组与健康人群比较,抗体阳性率的差异无统计学意义(χ2=1.18,P=0.27)。结论结核抗体测定对结核病的阳性检出率较高,优于传统的痰涂片和PPD实验检测,临床上具有很大的应用价值。
目的:探討血清結覈桿菌抗體檢測在住院患者結覈病診斷中的臨床價值。方法150例結覈病患者,80例非結覈病患者以及40例健康誌願者均應用以脂阿拉伯甘露糖(LAM)為抗原的 ELISA法進行抗體暘性率的檢測。併應用痰塗片和PPD實驗檢查對150例結覈患者進行檢測。結果在150例肺結覈患者中,結覈桿菌抗體檢測的暘性檢齣率為72.67%(109/150),顯著高于痰塗片的51.33%(77/150)和PPD實驗的58.67%(88/150),且差異均具有統計學意義(χ2=14.49,6.52;P<0.001,0.011)。結覈病組抗體暘性率總數為72.67%(109/150),顯著高于非結覈病組的17.50%(14/80)和健康對照組的10.00%(4/40),且與二者比較,差異均具有統計學意義(χ2=41.15,51.45;P<0.001,0.001)。非結覈疾病組與健康人群比較,抗體暘性率的差異無統計學意義(χ2=1.18,P=0.27)。結論結覈抗體測定對結覈病的暘性檢齣率較高,優于傳統的痰塗片和PPD實驗檢測,臨床上具有很大的應用價值。
목적:탐토혈청결핵간균항체검측재주원환자결핵병진단중적림상개치。방법150례결핵병환자,80례비결핵병환자이급40례건강지원자균응용이지아랍백감로당(LAM)위항원적 ELISA법진행항체양성솔적검측。병응용담도편화PPD실험검사대150례결핵환자진행검측。결과재150례폐결핵환자중,결핵간균항체검측적양성검출솔위72.67%(109/150),현저고우담도편적51.33%(77/150)화PPD실험적58.67%(88/150),차차이균구유통계학의의(χ2=14.49,6.52;P<0.001,0.011)。결핵병조항체양성솔총수위72.67%(109/150),현저고우비결핵병조적17.50%(14/80)화건강대조조적10.00%(4/40),차여이자비교,차이균구유통계학의의(χ2=41.15,51.45;P<0.001,0.001)。비결핵질병조여건강인군비교,항체양성솔적차이무통계학의의(χ2=1.18,P=0.27)。결론결핵항체측정대결핵병적양성검출솔교고,우우전통적담도편화PPD실험검측,림상상구유흔대적응용개치。
Objective To explore the value of Mycobacterium tuberculosis serum antibody detection in hospitalized patients with tuberculosis.Methods 150 tuberculosis patients,80 non tuberculosis patients and 40 healthy volunteers used LAM detection method for ELISA antigen positive rate of antibody.And sputum smear and PPD test were detec-ted in 150 cases of tuberculosis patients.Results in 150 cases of pulmonary tuberculosis patients,the detection of tu-bercular antibody positive rate was 72.67% (109/150),significantly higher than that of sputum smears 51.33% (77/150)and PPD 58.67% (88/150),and the differences were statistically significant (χ2=14.49,6.52;P<0.001, 0.011).The total positive rate of tuberculosis antibody was 72.67% (109/150),significantly higher than that of non tuberculosis 17.50% (14/80)and healthy control group10%(4/40),and compared with two,the differences were sta-tistically significant (χ2=41.15,51.45;P<0.001,0.001).Comparison of non tuberculosis disease group and the healthy group,there was no significant difference of positive rate of antibody (χ2=1.18,P=0.27).Conclusion tuber-culosis antibody has high positive detection rate in tuberculosis,better than sputum smear and PPD test,has great appli-cation value in clinic.