CAJ | 학술논문

内阿米巴属原虫是可寄生于人和动物肠道及其他内脏器官的人兽共患原虫，属内种类较多，但致病性种类主要是溶组织内阿米巴，可引起人和动物出现痢疾和肝脓肿，严重者可危及生命。致病性和非致病性的内阿米巴属原虫的包囊和滋养体在形态上很难区别，且同种的致病性、感染力等也存在一定的差异，因此，临床上传统的诊断方法很难确定病原的种类，相应也直接影响了临床用药，为了解内阿米巴属原虫的种类分布及其分型情况，本文就内阿米巴属原虫分子检测及基因分型方法的研究进展情况进行综述。
내아미파속원충시가기생우인화동물장도급기타내장기관적인수공환원충，속내충류교다，단치병성충류주요시용조직내아미파，가인기인화동물출현이질화간농종，엄중자가위급생명。치병성화비치병성적내아미파속원충적포낭화자양체재형태상흔난구별，차동충적치병성、감염력등야존재일정적차이，인차，림상상전통적진단방법흔난학정병원적충류，상응야직접영향료림상용약，위료해내아미파속원충적충류분포급기분형정황，본문취내아미파속원충분자검측급기인분형방법적연구진전정황진행종술。
Entamoeba is a zoonotic protozoan that can parasitize in the intestine and other organs in human and animals . There are many species in this genus ,but only Entamoeba histolytica can cause amebic colitis and liver abscess ,and even death .The cysts and trophozoits are difficult to be discriminated for pathogenic and nonpathogenic Entamoeba .And there is al-so difference in the pathogenicity ,infectivity etc .,even in the same species .Therefore ,it is difficult to confirm the Entamoeba species according to traditional method ,thus affecting the use of medicine .In this article ,the research progress of molecular examination and genotyping method about entamoeba are reviewed .