中国处方药
中國處方藥
중국처방약
CHINA PRESCRIPTION DRUG
2014年
7期
36-37
,共2页
符祥瑜%苏格萍%刘新庆
符祥瑜%囌格萍%劉新慶
부상유%소격평%류신경
奥美拉唑%清洁残留%紫外分光光度法%验证
奧美拉唑%清潔殘留%紫外分光光度法%驗證
오미랍서%청길잔류%자외분광광도법%험증
Omeprazole%Cleaning residue%UV Spectrophotometry%Validation
目的：验证紫外分光光度法测定奥美拉唑清洁残留物的准确性。方法以0.1 mol/L NaOH溶液为溶剂，采用紫外分光光度法，检测波长为305 nm。结果该检验方法在2～16μg/mL范围有较好线性关系，准确度与精密度分别为0.5%、0.3%，检测限与定量限分别为0.045μg/mL、0.14μg/mL。擦拭法的回收率大于70.92%。结论此方法简单易操作，准确度、精密度良好。
目的：驗證紫外分光光度法測定奧美拉唑清潔殘留物的準確性。方法以0.1 mol/L NaOH溶液為溶劑，採用紫外分光光度法，檢測波長為305 nm。結果該檢驗方法在2～16μg/mL範圍有較好線性關繫，準確度與精密度分彆為0.5%、0.3%，檢測限與定量限分彆為0.045μg/mL、0.14μg/mL。抆拭法的迴收率大于70.92%。結論此方法簡單易操作，準確度、精密度良好。
목적：험증자외분광광도법측정오미랍서청길잔류물적준학성。방법이0.1 mol/L NaOH용액위용제，채용자외분광광도법，검측파장위305 nm。결과해검험방법재2～16μg/mL범위유교호선성관계，준학도여정밀도분별위0.5%、0.3%，검측한여정량한분별위0.045μg/mL、0.14μg/mL。찰식법적회수솔대우70.92%。결론차방법간단역조작，준학도、정밀도량호。
Objective To validate the accuracy of determination of cleaning residue in omeprazole by UV Spectrophotometry.Methods 0.1 mol/L NaOH solution was used as solvent. UV spectrophotometry was used and its detective wave length was 305 nm.Results It was good linear relationship in the rang of 2~16μg/mL The accuracy was 0.5%, and the precision was 0.3%. The limit of detection and limit of quantification were 0.045μg/mLand 0.14μg/mL Wiping the recovery rate was more than 70.92%.Conclusion UV Spectrophotometry is a simple and an easy way to detect the cleaning residue in omeprazole with high accuracy and good precision.
