CAJ | 학술논문

目的：探讨早孕孕妇血清β-HCG及孕酮检测水平与胎儿生长发育状况的关系。方法用深圳产MAGLUMI1000全自动化学发光测定仪检测142例正常早孕孕妇和58例胎儿发育不良、停止发育等非正常早孕孕妇的血清β-HCG和孕酮水平，同时做彩色B超检查；48 h后再次检测血清β-HCG水平，对有流血等先兆流产孕妇进行保胎治疗并密切观察。结果非正常早孕孕妇的血清β-HCG与孕酮水平明显低于正常妊娠妇女且增长速度较慢（P＜0.05），绝大部分正常妊娠妇女（94.6%）血清β-HCG水平的倍增＜2 d，而大部分非正常妊娠妇女（85.7%）血清β-HCG水平的倍增＞2 d。早孕孕妇的血清β-HCG与孕酮水平与胎儿生长发育状况成正相关，当血清β-HCG和孕酮平均水平分别达31601 IU/L和20.8 ng/mL时，容易保胎成功。结论非正常妊娠妇女血清β-HCG与孕酮水平明显低于正常妊娠妇女且增长速度较慢。
목적：탐토조잉잉부혈청β-HCG급잉동검측수평여태인생장발육상황적관계。방법용심수산MAGLUMI1000전자동화학발광측정의검측142례정상조잉잉부화58례태인발육불량、정지발육등비정상조잉잉부적혈청β-HCG화잉동수평，동시주채색B초검사；48 h후재차검측혈청β-HCG수평，대유류혈등선조유산잉부진행보태치료병밀절관찰。결과비정상조잉잉부적혈청β-HCG여잉동수평명현저우정상임신부녀차증장속도교만（P＜0.05），절대부분정상임신부녀（94.6%）혈청β-HCG수평적배증＜2 d，이대부분비정상임신부녀（85.7%）혈청β-HCG수평적배증＞2 d。조잉잉부적혈청β-HCG여잉동수평여태인생장발육상황성정상관，당혈청β-HCG화잉동평균수평분별체31601 IU/L화20.8 ng/mL시，용역보태성공。결론비정상임신부녀혈청β-HCG여잉동수평명현저우정상임신부녀차증장속도교만。
Objective To study the relationship between the serum levels of β-human chorionic gonadotrophin(HCG) and progesterone and the growth and development status of fetal in early pregnant women.Methods The levels of serum β-HCG and progesterone were analyzed among 142 normal pregnant women and 58 abnormal early pregnant women(fetal dysplasia, stop development). The same test was repeated 48 hours later. A tocolysis therapy and follow up were conducted among the abnormal early pregnant women.Results A positive relationship between the levels of serumβ-HCG and progesterone and status of fetal development was observed. The levels of serumβ-HCG and progesterone are much lower among the abnormal early pregnant women than the normal ones, and the serumβ-HCG in abnormal early pregnant women growths significantly slow. Among most of the normal pregnant women(94.6%), the multiplication of serumβ-HCG was found<2 days. However, among most of the abnormal early pregnant women(85.7%), the multiplication was found more than 2 days. It is easy to conduct a successful fetus protection when the mean levels of the serum β-HCG and progesterone reach 31 601 IU/L and 20.8ng/mL respectively.Conclusion Among the abnormal early pregnant women, the levels of the serum β-HCG and progesterone are much lower than normal early pregnant women, and the multiplication ofβ-HCG is significantly slow than the normal ones.