CAJ | 학술논문

功能性消化不良（ functional dyspepsia ， FD）是一种常见的功能性胃肠道疾病，造成FD的病因目前尚未完全阐明。生长激素释放肽（ Ghrelin）是一种主要由胃的内分泌细胞（ X/A样细胞）分泌的脑肠肽。受体在体内广泛分布，具有调节生长激素分泌、摄食和能量平衡，影响神经内分泌及胃肠功能等多种生物学作用。越来越多的研究表明Ghrelin在FD中对于提高摄食量、产生饥饿感及促进胃排空方面有积极作用。目前，Ghrelin已成为研究FD的新热点。
공능성소화불량（ functional dyspepsia ， FD）시일충상견적공능성위장도질병，조성FD적병인목전상미완전천명。생장격소석방태（ Ghrelin）시일충주요유위적내분비세포（ X/A양세포）분비적뇌장태。수체재체내엄범분포，구유조절생장격소분비、섭식화능량평형，영향신경내분비급위장공능등다충생물학작용。월래월다적연구표명Ghrelin재FD중대우제고섭식량、산생기아감급촉진위배공방면유적겁작용。목전，Ghrelin이성위연구FD적신열점。
Functional dyspepsia is a common functional gastrointestinal disease , however , the cause of functional dyspepsia has not been fully elucidated .Ghrelin is braingut petide , secreted by major endocrine cells of the stomach ( x/A like cells ) .Its recep-tor is widely distributed in the body .It has many kinds of biological effects , such as regulating growth hormone secretion , feeding and energy balance , affecting neuroendocrine and gastrointestinal function and so on .A growing number of studies have shown that Ghrelin in FD has a positive role in increasing the improvement of food intake and generating hunger , promoting gastric emptying .Ghrelin is a new hot spot in the research of FD .