CAJ | 학술논문

目的：探讨缺血修饰蛋白与脂蛋白相关磷脂酶A2两项指标在动脉硬化性脑梗死（ACI）中的应用价值。方法对脑梗死组130例和对照组120例的血清缺血修饰蛋白（IMA）、脂蛋白相关磷脂酶A2（Lp-PLA2）进行平行检测，并做对比分析。结果脑梗死组IMA、Lp-PLA2表达水平均高于对照组。结论血清IMA、Lp-PLA2水平增高与ACI密切相关，及早检测血清IMA、Lp-PLA2等相关指标，对动脉硬化性脑梗死的预防及治疗有着非常积极的意义。
목적：탐토결혈수식단백여지단백상관린지매A2량항지표재동맥경화성뇌경사（ACI）중적응용개치。방법대뇌경사조130례화대조조120례적혈청결혈수식단백（IMA）、지단백상관린지매A2（Lp-PLA2）진행평행검측，병주대비분석。결과뇌경사조IMA、Lp-PLA2표체수평균고우대조조。결론혈청IMA、Lp-PLA2수평증고여ACI밀절상관，급조검측혈청IMA、Lp-PLA2등상관지표，대동맥경화성뇌경사적예방급치료유착비상적겁적의의。
Objective Study the ischemia modified protein and lipoprotein associated phospholipase A 2 two indicators in arteriosclerotic cerebral infarction (ACI) application value. Methods One hundred and thirty cases of cerebral infarction group and control serum ischemia modified albumin group 120 cases (IMA), lipoprotein associated phospholipase A2(Lp-PLA2) for parallel detection, and do comparative analysis. Results The expression levels of IMA, Lp-PLA2 in cerebral infarction group were significantly higher than control group. Conclusion Serum IMA, Lp-PLA2 levels are closely related with ACI, early detection of serum IMA, Lp-PLA2 and other related indicators, has a very positive significance for the prevention and treatment of arteriosclerotic cerebral infarction.