临床肿瘤学杂志
臨床腫瘤學雜誌
림상종류학잡지
CHINESE CLINICAL ONCOLOGY
2014年
7期
667-670
,共4页
杨佳程%蔡讯(综述)%王理伟(审校)
楊佳程%蔡訊(綜述)%王理偉(審校)
양가정%채신(종술)%왕리위(심교)
C反应蛋白( CRP )%炎症%胰腺癌%化学治疗%姑息治疗%生存期
C反應蛋白( CRP )%炎癥%胰腺癌%化學治療%姑息治療%生存期
C반응단백( CRP )%염증%이선암%화학치료%고식치료%생존기
C-reactive protein%Inflammation%Pancreatic cancer%Chemotherapy%Palliative treatment%Survival
血清C反应蛋白( CRP )是一个特异性不高但具有高度灵敏度的炎症指标。目前已广泛应用于临床疾病的诊断及对预后的判断。近10年来,CRP对肿瘤预后的预测作用引起了较多学者的关注,已有研究证实血清CRP水平与肿瘤的生存期相关。本文综述了术前、术后、化疗前及姑息治疗前血清CRP水平对胰腺癌生存期的预测作用,尽管结果尚存在争议,但部分研究表明术后、晚期一线化疗前及姑息性治疗前升高的血清CRP水平均提示预后不良。
血清C反應蛋白( CRP )是一箇特異性不高但具有高度靈敏度的炎癥指標。目前已廣汎應用于臨床疾病的診斷及對預後的判斷。近10年來,CRP對腫瘤預後的預測作用引起瞭較多學者的關註,已有研究證實血清CRP水平與腫瘤的生存期相關。本文綜述瞭術前、術後、化療前及姑息治療前血清CRP水平對胰腺癌生存期的預測作用,儘管結果尚存在爭議,但部分研究錶明術後、晚期一線化療前及姑息性治療前升高的血清CRP水平均提示預後不良。
혈청C반응단백( CRP )시일개특이성불고단구유고도령민도적염증지표。목전이엄범응용우림상질병적진단급대예후적판단。근10년래,CRP대종류예후적예측작용인기료교다학자적관주,이유연구증실혈청CRP수평여종류적생존기상관。본문종술료술전、술후、화료전급고식치료전혈청CRP수평대이선암생존기적예측작용,진관결과상존재쟁의,단부분연구표명술후、만기일선화료전급고식성치료전승고적혈청CRP수평균제시예후불량。
C-reactive protein(CRP) is a nonspecific but sensitive marker suggesting inflammation. It has been most widely used for clinical diagnosis and prognosis of cardiovascular diseases. In the last decade, the prediction of CRP in cancer has caused more and more attention from many scholars. A lot of research have demonstrated that elevated CRP level is a determinant predictor of lower sur-vival rates in patients with several cancers such as gastrointestinal cancer and gynecologic tumor. In this review, we briefly summarize the prognostic values of preoperative and postoperative serum CRP levels in resectable pancreatic cancer, and of the pretherapeutic CRP levels in advanced pancreatic carcinoma, respectively. Although the results are still controversial, an elevated CRP, measured ei-ther postoperative or pretherapeutic, has been shown to predict poor survival in some clinical researches.