CAJ | 학술논문

以丹皮为原料提取丹皮总黄酮，并测得其在丹皮中的含量为1.6304％。以常用的化学合成抗氧化剂2，6-二叔丁基-4-甲基苯酚（BHT）和叔丁基对苯二酚（TBHQ）为对照，通过4种方法评价了丹皮总黄酮的抗氧化活性。结果表明，在相同浓度条件下，丹皮总黄酮对羟基自由基（·OH）清除率＞对 DPPH 自由基（·DPPH）清除率＞对超氧阴离子自由基（·O-2）清除率＞对小鼠肝组织脂质过氧化的抑制率；丹皮总黄酮具有较强的抗氧化能力，其抗氧化活性略低于或等于TBHQ的抗氧化活性，远远大于 BHT的抗氧化活性，在较低浓度下即具有对多种氧化反应的抑制作用。表明，丹皮总黄酮是一种很有发展前景的天然抗氧化剂。
이단피위원료제취단피총황동，병측득기재단피중적함량위1.6304％。이상용적화학합성항양화제2，6-이숙정기-4-갑기분분（BHT）화숙정기대분이분（TBHQ）위대조，통과4충방법평개료단피총황동적항양화활성。결과표명，재상동농도조건하，단피총황동대간기자유기（·OH）청제솔＞대 DPPH 자유기（·DPPH）청제솔＞대초양음리자자유기（·O-2）청제솔＞대소서간조직지질과양화적억제솔；단피총황동구유교강적항양화능력，기항양화활성략저우혹등우TBHQ적항양화활성，원원대우 BHT적항양화활성，재교저농도하즉구유대다충양화반응적억제작용。표명，단피총황동시일충흔유발전전경적천연항양화제。
Total flavonoids were extracted from Tree peony bark,whose content accounting for Tree peony bark(dry mass)was 1.6304%.The antioxidant activities of total flavonoids were also studied through four methods with two commonly used antioxidants BHT and TBHQ as control compounds.Results showed that, the total flavonoids had the antioxidant activity following the order as follows:·OH scavenging rate>·DPPH scavenging rate >·O-2 scavenging rate>the inhibition rate of lipid peroxidation in mouse liver issue.The total flavonoids from Tree peony bark had strong antioxidant activity,which was slightly lower than TBHQ,but far greater than that of BHT.At lower concentration,the total flavonoids can inhibit several oxidation reactions, which showed that total flavonoids from Tree peony bark was a promising natural antioxidant.