西部中医药
西部中醫藥
서부중의약
GANSU JOURNAL OF TRADITIONAL CHINESE MEDICINE
2014年
7期
1-3
,共3页
苏筠霞%徐筠%苏建平%李建华%刘明龙
囌筠霞%徐筠%囌建平%李建華%劉明龍
소균하%서균%소건평%리건화%류명룡
肾病,尿酸性%UA%BUN%Cr%L-FABP%复方萆薢汤%别嘌呤醇
腎病,尿痠性%UA%BUN%Cr%L-FABP%複方萆薢湯%彆嘌呤醇
신병,뇨산성%UA%BUN%Cr%L-FABP%복방비해탕%별표령순
nephropathy,uric acid%UA%BUN%Cr%L-FABP%compoundBiXieTang%allopurinol
目的:观察复方萆薢汤治疗尿酸性肾病的临床疗效。方法:将尿酸性肾病患者46例随机分为复方萆薢汤组(n=24)与别嘌呤醇组(n=22)。复方萆薢汤组予复方萆薢汤治疗,别嘌呤醇组予别嘌呤醇治疗,并于治疗前及治疗8周后检测2组患者血清尿酸(UA)、尿素氮(BUN)、肌酐(Cr)水平,于采血前24小时留取2组患者尿液检测24小时尿蛋白定量和尿肝脏型脂肪酸结合蛋白(L-FABP)定量。结果:复方萆薢汤组患者血清UA、BUN、Cr水平改善明显(P<0.05),效果优于别嘌呤醇组(P<0.05);复方萆薢汤组患者24小时尿蛋白定量和尿L-FABP明显减少,效果优于别嘌呤醇组,2组比较差异有统计学意义(P<0.05)。结论:复方萆薢汤能提高尿酸性肾病的临床疗效,并具有保护肾功能的作用。
目的:觀察複方萆薢湯治療尿痠性腎病的臨床療效。方法:將尿痠性腎病患者46例隨機分為複方萆薢湯組(n=24)與彆嘌呤醇組(n=22)。複方萆薢湯組予複方萆薢湯治療,彆嘌呤醇組予彆嘌呤醇治療,併于治療前及治療8週後檢測2組患者血清尿痠(UA)、尿素氮(BUN)、肌酐(Cr)水平,于採血前24小時留取2組患者尿液檢測24小時尿蛋白定量和尿肝髒型脂肪痠結閤蛋白(L-FABP)定量。結果:複方萆薢湯組患者血清UA、BUN、Cr水平改善明顯(P<0.05),效果優于彆嘌呤醇組(P<0.05);複方萆薢湯組患者24小時尿蛋白定量和尿L-FABP明顯減少,效果優于彆嘌呤醇組,2組比較差異有統計學意義(P<0.05)。結論:複方萆薢湯能提高尿痠性腎病的臨床療效,併具有保護腎功能的作用。
목적:관찰복방비해탕치료뇨산성신병적림상료효。방법:장뇨산성신병환자46례수궤분위복방비해탕조(n=24)여별표령순조(n=22)。복방비해탕조여복방비해탕치료,별표령순조여별표령순치료,병우치료전급치료8주후검측2조환자혈청뇨산(UA)、뇨소담(BUN)、기항(Cr)수평,우채혈전24소시류취2조환자뇨액검측24소시뇨단백정량화뇨간장형지방산결합단백(L-FABP)정량。결과:복방비해탕조환자혈청UA、BUN、Cr수평개선명현(P<0.05),효과우우별표령순조(P<0.05);복방비해탕조환자24소시뇨단백정량화뇨L-FABP명현감소,효과우우별표령순조,2조비교차이유통계학의의(P<0.05)。결론:복방비해탕능제고뇨산성신병적림상료효,병구유보호신공능적작용。
Objective: To investigate therapeutic effects of compoundBiXieTangin treating uric acid nephropathy(UAN). Methods: All 46 patients were randomized into compoundBiXieTanggroup(n=24) and allopurinol group(n=22). CompoundBiXieTanggroup took compoundBiXieTangand allopurinol group allopurinol, the levels of uric acid (UA) in the serum, blood urea nitrogen(BUN) and creatinine(Cr) of the patients in both groups were detected before treating and in eight weeks after treating, the urines of the patients were kept in 24 hours before drawing the blood, quantitative tests for 24 hours urine protein and liver fatty acid binding protein (L-FABP) in urine were performed. Results: The levels of UA, BUN and Cr of compoundBiXieTanggroup were improved notably(P<0.05), compoundBiXieTangwas superior to allopurinol(P<0.05); quantitative tests for 24 hours urine protein and L-FABP in urine of compoundBiXieTanggroup showed that they were lowered significantly, the decoction showed better effects compared with allopurinol, the difference had statistical meaning (P<0.05). Conclusion: CompoundBiXieTangcould raise therapeutic effects of treatment for UAN, and it could protect renal function.