安徽医学
安徽醫學
안휘의학
ANHUI MEDICAL JOURNAL
2014年
7期
943-945
,共3页
中心静脉导管%恶性胸腔积液%白介素-2%顺铂
中心靜脈導管%噁性胸腔積液%白介素-2%順鉑
중심정맥도관%악성흉강적액%백개소-2%순박
Central venous catheter%Malignant pleural effusion%Iterleukin-2%Cisplatin
目的：观察置管引流后灌注白介素-2联合顺铂治疗恶性胸腔积液的疗效。方法将56例恶性胸腔积液患者随机分为治疗组和对照组，治疗组28例，对照组28例。两组均置入中心静脉导管，待胸水引流完后，治疗组胸腔内灌注白介素-2（200万U ）和顺铂（80 mg/m2），对照组胸腔内仅灌注顺铂（80 mg/m2）。结果治疗组总有效率为85．7％，对照组总有效率为64．3％，两组差异有统计学意义（P＜0．05）。结论胸腔内灌注白介素-2联合顺铂治疗恶性胸腔积液是一种疗效肯定、经济安全的方法，且毒副作用小。
目的：觀察置管引流後灌註白介素-2聯閤順鉑治療噁性胸腔積液的療效。方法將56例噁性胸腔積液患者隨機分為治療組和對照組，治療組28例，對照組28例。兩組均置入中心靜脈導管，待胸水引流完後，治療組胸腔內灌註白介素-2（200萬U ）和順鉑（80 mg/m2），對照組胸腔內僅灌註順鉑（80 mg/m2）。結果治療組總有效率為85．7％，對照組總有效率為64．3％，兩組差異有統計學意義（P＜0．05）。結論胸腔內灌註白介素-2聯閤順鉑治療噁性胸腔積液是一種療效肯定、經濟安全的方法，且毒副作用小。
목적：관찰치관인류후관주백개소-2연합순박치료악성흉강적액적료효。방법장56례악성흉강적액환자수궤분위치료조화대조조，치료조28례，대조조28례。량조균치입중심정맥도관，대흉수인류완후，치료조흉강내관주백개소-2（200만U ）화순박（80 mg/m2），대조조흉강내부관주순박（80 mg/m2）。결과치료조총유효솔위85．7％，대조조총유효솔위64．3％，량조차이유통계학의의（P＜0．05）。결론흉강내관주백개소-2연합순박치료악성흉강적액시일충료효긍정、경제안전적방법，차독부작용소。
Objective To observe the therapeutic effect in the treatment of malignant pleural effusion by using interleukin-2 with cis-platin through thoracic cavity perfusion drainage.Methods 56 cases patients with malignant pleural effusion were randomly divided into the therapy group and the control group.The therapy group 28 cases,the control group 28 cases.All patients were embedded with a central venous catheter,after drainage,interleukin-2(2000000u)with cisplatin(80mg/m2 )were injected into pleural cavity in the therapy group,only cispla-tin(80mg/m2)were injected into pleural cavity in the control group.Results Total effective rat were 85.7% in the therapy group,and 64.3% in the control group.There was significant difference between them(P<0.05).Conclusion The treatment of using interleukin-2 with cisplatin though thoracic tube is regarded as effective、well tolerated for malignant pleural effusion,and the side effect is minor.
