CAJ | 학술논문

目的：探讨进展性脑梗死与血浆D-二聚体（D-D）、纤维蛋白原及其降解产物含量的关系。方法采用免疫比浊法测定血浆D-二聚体和纤维蛋白原，乳胶凝聚法测定纤维蛋白原降解产物（FDP）含量。比较进展性脑梗死、非进展性脑梗死及健康对照组之间的差异。结果脑梗死组在D-二聚体、纤维蛋白原及其降解产物含量明显高于健康对照组，与之比较差异有统计学意义（P＜0．05），进展性脑梗死高于非进展性脑梗死（P＜0．05）。结论进展性脑梗死患者存在着明显的高凝状态，这与其发生及病情进展密切相关。
목적：탐토진전성뇌경사여혈장D-이취체（D-D）、섬유단백원급기강해산물함량적관계。방법채용면역비탁법측정혈장D-이취체화섬유단백원，유효응취법측정섬유단백원강해산물（FDP）함량。비교진전성뇌경사、비진전성뇌경사급건강대조조지간적차이。결과뇌경사조재D-이취체、섬유단백원급기강해산물함량명현고우건강대조조，여지비교차이유통계학의의（P＜0．05），진전성뇌경사고우비진전성뇌경사（P＜0．05）。결론진전성뇌경사환자존재착명현적고응상태，저여기발생급병정진전밀절상관。
Objective To observe the plasma levels of D-dimer(D-D)and fibrinogen(Fib)in progressing ischemic stroke.Methods The D-D and Fib level were determined by immunotur-bidimetry.Compare with the D-D and Fib level in Progressing Ischemic Stroke,not Progressing Ischemic Stroke and control group.Results D-D and Fib contents in ischemic stroke group were significantly higher than those in control group(P<0.05 ).D-D and Fib contents in Progressing Ischemic Stroke group were higher than those in not Progressing Ischemic Stroke group,D-D and Fib contents in not Progressing Ischemic Stroke were higher than those in control group(P<0.05 ).Conclusion There is a high coagulative satuation in Progressing Ischemic Stroke.It is positive correlation between them.