CAJ | 학술논문

目的：通过全身亚低温治疗多器官功能障碍综合征（MODS）患儿，探讨全身亚低温技术对MODS患儿呼吸功能的影响。方法将36例MODS患儿随机分为全身亚低温治疗组（亚低温组，19例）和常规治疗组（对照组，17例）。分别在治疗前、第12、24和36小时时间点测量记录两组患儿基本生命体征和血气的变化。结果亚低温组和对照组呼吸频率（R）、二氧化碳分压（PCO2）、乳酸（LAC）治疗前与第36小时比较均有统计学意义（P＜0．05）；第36小时，两组之间PCO2比较差异有统计学意义（P＜0．05）；第12小时和第36小时，两组之间LAC比较差异有统计学意义（P＜0．05）；亚低温组，LAC治疗前与第36小时比较差异有统计学意义（P＜0．05）；第24小时，两组之间R比较有统计学意义（P＜0．05）；亚低温组，治疗前与第24、36小时SpO2比较差异均有统计学意义（P＜0．05）；pH值、PaO2在各时间段组间及组内比较差异均无统计学意义（P＞0．05）。结论全身亚低温治疗对MODS患儿呼吸功能具有保护作用。
목적：통과전신아저온치료다기관공능장애종합정（MODS）환인，탐토전신아저온기술대MODS환인호흡공능적영향。방법장36례MODS환인수궤분위전신아저온치료조（아저온조，19례）화상규치료조（대조조，17례）。분별재치료전、제12、24화36소시시간점측량기록량조환인기본생명체정화혈기적변화。결과아저온조화대조조호흡빈솔（R）、이양화탄분압（PCO2）、유산（LAC）치료전여제36소시비교균유통계학의의（P＜0．05）；제36소시，량조지간PCO2비교차이유통계학의의（P＜0．05）；제12소시화제36소시，량조지간LAC비교차이유통계학의의（P＜0．05）；아저온조，LAC치료전여제36소시비교차이유통계학의의（P＜0．05）；제24소시，량조지간R비교유통계학의의（P＜0．05）；아저온조，치료전여제24、36소시SpO2비교차이균유통계학의의（P＜0．05）；pH치、PaO2재각시간단조간급조내비교차이균무통계학의의（P＞0．05）。결론전신아저온치료대MODS환인호흡공능구유보호작용。
Objective To investigate the effect of systemic hypothermia technique MODS respiratory function in children with sys-temic hypothermia treatment.Methods MODS patients were randomly divided into 36 cases of mild hypothermia group (treatment group)19 patients and the control group (control group)17 cases.Before each treatment,the first 12h,24h,36h time measuring and recording changes in vital signs and basic blood groups of children.Results Before treatment with the first 36 hours,hypothermia group and the control group respiratory rate (R),carbon dioxide partial pressure (PCO2),lactate (LAC)were statistically significance (P <0.05);The first 36 hours, PCO2 difference between the two groups was statistically significance (P <0.05);The first 12 hours and 36 hours,LAC difference between the two groups were statistically significance (P <0.05);In mild hypothermia group,LAC pre-treatment with the first 36 hours was statisti-cally significance (P<0.05);The first 24 hours,R between the two groups was statistically significance(P<0.05);In hypothermia treatment group,pre-treatment with the first 24,36 hours SpO2 differences were statistically significance (P <0.05);PH value,PaO2 between groups at each time and within groups were no significant difference (P>0.05 ).Conclusion MODS systemic hypothermia therapy on respiratory function in children has a protective effection.