CAJ | 학술논문

妊娠期高血压疾病是围产期常见的并发症。胰岛素抵抗是指正常浓度胰岛素的生理效应低于正常，妊娠期发生生理性胰岛素抵抗，胰岛素抵抗加重引起一系列代谢异常并与妊娠期高血压疾病的发生相关。FFA、炎性因子、脂肪因子等可能同时参与胰岛素抵抗及妊娠期高血压疾病的发病。
임신기고혈압질병시위산기상견적병발증。이도소저항시지정상농도이도소적생리효응저우정상，임신기발생생이성이도소저항，이도소저항가중인기일계렬대사이상병여임신기고혈압질병적발생상관。FFA、염성인자、지방인자등가능동시삼여이도소저항급임신기고혈압질병적발병。
Hypertensive disorders complicating pregnancy is a common complication in perinatal period. Insulin resistance refers to the physiological effect of normal concentration of insulin lower than that in normal. Physiological insulin resistance exists during pregnancy. Insulin resistance increasing causes a series of metabolic abnormalities associated with pregnancy induced hypertension. FFA, inflammatory cytokines, adipokines may also participate in the insulin resistance and the incidence of hypertensive disorder complicating pregnancy.