临床医学
臨床醫學
림상의학
CLINICAL MEDICINE
2014年
8期
18-19
,共2页
食管肿瘤%照射野%累积野照射%选择淋巴引流区照射
食管腫瘤%照射野%纍積野照射%選擇淋巴引流區照射
식관종류%조사야%루적야조사%선택림파인류구조사
Esophageal cancer%Radiation field%Involved field radiotherapy%Selected lymphatic drainage field radiotherapy
目的：比较局部晚期食管癌累积野照射与选择淋巴引流区照射的毒性反应与疗效。方法将60例局部晚期食管鳞癌患者按照数字表法随机分成两组：累积野照射组和选择淋巴引流区照射组。两组PTV照射50.4 Gy，共28次， PGTV照射59.36 Gy，共28次。两组均同期给予DF方案化疗2个周期。结果累积野照射组和选择淋巴引流区照射组1、2生存率分别是83%、65%和80%、59%，差异无统计学意义（χ2=0.064，P=0.317）。累积野照射组和选择淋巴引流区照射组有效率分别为93.3%（28/30）和96.6%（29/30），差异无统计学意义（χ2=0.867，P=0.335）。急性不良反应两组比较差异无统计学意义。结论局部晚期食管癌放射治疗时采用累积野照射与选择淋巴引流区照射疗效相同，急性不良反应相同，应进一步观察晚期损伤，放疗中应使用照射野较小的累积野照射。
目的：比較跼部晚期食管癌纍積野照射與選擇淋巴引流區照射的毒性反應與療效。方法將60例跼部晚期食管鱗癌患者按照數字錶法隨機分成兩組：纍積野照射組和選擇淋巴引流區照射組。兩組PTV照射50.4 Gy，共28次， PGTV照射59.36 Gy，共28次。兩組均同期給予DF方案化療2箇週期。結果纍積野照射組和選擇淋巴引流區照射組1、2生存率分彆是83%、65%和80%、59%，差異無統計學意義（χ2=0.064，P=0.317）。纍積野照射組和選擇淋巴引流區照射組有效率分彆為93.3%（28/30）和96.6%（29/30），差異無統計學意義（χ2=0.867，P=0.335）。急性不良反應兩組比較差異無統計學意義。結論跼部晚期食管癌放射治療時採用纍積野照射與選擇淋巴引流區照射療效相同，急性不良反應相同，應進一步觀察晚期損傷，放療中應使用照射野較小的纍積野照射。
목적：비교국부만기식관암루적야조사여선택림파인류구조사적독성반응여료효。방법장60례국부만기식관린암환자안조수자표법수궤분성량조：루적야조사조화선택림파인류구조사조。량조PTV조사50.4 Gy，공28차， PGTV조사59.36 Gy，공28차。량조균동기급여DF방안화료2개주기。결과루적야조사조화선택림파인류구조사조1、2생존솔분별시83%、65%화80%、59%，차이무통계학의의（χ2=0.064，P=0.317）。루적야조사조화선택림파인류구조사조유효솔분별위93.3%（28/30）화96.6%（29/30），차이무통계학의의（χ2=0.867，P=0.335）。급성불량반응량조비교차이무통계학의의。결론국부만기식관암방사치료시채용루적야조사여선택림파인류구조사료효상동，급성불량반응상동，응진일보관찰만기손상，방료중응사용조사야교소적루적야조사。
Objective To compare the toxicity and the curative effect of involved field radiotherapy( IFRT)and selected lym-phatic drainage field radiotherapy for local advanced esophageal cancer. Methods Sixty patients with local advanced esophageal squamous cell carcinoma were randomly divided into two groups according to random number table:involved field radiotherapy group and selected lymphatic drainage field radiotherapy group. Both groups got PTV irradiation 50. 4 Gy,a total of 28 times, PGTV irradiation 59. 36 Gy,and a total of 28 times. Both groups were given 2 cycles of chemotherapy with DF scheme. Results The 1-year and 2-year survival rate of involved field radiotherapy group was 83% and 65%,and the 1-year and 2-year survival rate of selected lymphatic drainage field radiotherapy group was 80% and 59%,there was no significant difference be-tween the two groups(χ2 =0. 064,P=0. 317). The effective rate of involved field radiotherapy group was 93. 3%(28/30),and was 96. 6%(29/30)of selected lymphatic drainage field radiotherapy group,there was no significant difference between the two groups(χ2 = 0. 867, P = 0. 335 ). There was no significant difference in acute toxicity between the two groups. Conclusion There is no significant difference in the curative effect or acute toxicity between involved field radiotherapy( IFRT) and selected lymphatic drainage field radiotherapy for local advanced esophageal cancer. Late lesion should be further observed. Radiation field should be small in involved field radiotherapy.
