CAJ | 학술논문

目的：分析外源性过敏性肺泡炎(EAA)的临床特点,提高对 EAA 的诊断和治疗能力。方法回顾性分析我院3例 EAA 患者的临床资料,分析和讨论 EAA 的发病机制、临床表现、诊断、治疗及预后等。结果3例患者中1例有明确的过敏原接触史,其余2例为较隐匿的间接接触史。临床症状主要有咳嗽、咳痰、发热和喘憋,其中1例为急性起病,其余2例为慢性起病。肺部高分辨 CT 主要表现为索条影、弥漫性斑片状或磨玻璃样影等。其中1例支气管肺泡灌洗液 CD4/CD8为4.13,其余2例分别为0.72和0.84。3例患者经治疗后症状均缓解。结论 EAA 患者临床表现、严重程度和自然病史差异性很大,起病缓急不一。当临床表现不典型,暴露因素不明确时需临床医师高度的识别能力。
목적：분석외원성과민성폐포염(EAA)적림상특점,제고대 EAA 적진단화치료능력。방법회고성분석아원3례 EAA 환자적림상자료,분석화토론 EAA 적발병궤제、림상표현、진단、치료급예후등。결과3례환자중1례유명학적과민원접촉사,기여2례위교은닉적간접접촉사。림상증상주요유해수、해담、발열화천별,기중1례위급성기병,기여2례위만성기병。폐부고분변 CT 주요표현위색조영、미만성반편상혹마파리양영등。기중1례지기관폐포관세액 CD4/CD8위4.13,기여2례분별위0.72화0.84。3례환자경치료후증상균완해。결론 EAA 환자림상표현、엄중정도화자연병사차이성흔대,기병완급불일。당림상표현불전형,폭로인소불명학시수림상의사고도적식별능력。
Objective To improve the ability of diagnosis and treatment of patients with extrinsic allergic alveolitis(EAA)upon the analysis of its clinical features.Methods We retrospectively analyzed the clinical data of three patients with EAA in our hospital,including pathogenesis,clinical manifestation,diagnosis,treatment and prognosis evaluation.Results One case had a clear allergen exposure history,the remaining two cases had the hidden history of indirect contact.Clinical symptoms mainly contained cough,sputum,fever,and wheezing.One patient had acute onset,and the other two cases had chronic onset.High-resolution CT lung manifestation mainly contained streaks shadow,diffuse or patchy ground-glass opacities and so on,the CD4/CD8 in the bronchoalveolar lavage fluid of one patient was 4.13,while that in the remaining two cases was 0.72 and 0.84.Three patients were alleviated in symptoms after treatment.Conclusion The clinical manifestation,severity and natural history of patients with EAA have a variety of performances.Clinicians need high recognised ability especially when patients have atypical clinical manifestations or the exposure factors of patients are not clear.