CAJ | 학술논문

目的：评价颅内血肿微创清除术联合依达拉奉治疗高血压性脑出血的临床疗效。方法检索Medline数据库、Embase数据库、Cochrane图书馆、中国生物医学文献数据库、万方数据库、维普资讯网、中国期刊全文数据库，收集所有颅内血肿微创清除术联合依达拉奉治疗高血压性脑出血的临床随机对照试验（ RCT），对符合纳入标准的临床研究进行Meta分析。结果共纳入9个随机对照试验，Meta分析结果显示，颅内血肿微创清除术联合依达拉奉组治疗高血压性脑出血总有效率高于微创治疗组（P＜0．05），死亡率低于微创治疗组（P＜0．05）。结论颅内血肿微创清除术联合依达拉奉治疗高血压性脑出血能提高疗效，降低患者死亡率及提高生存质量。
목적：평개로내혈종미창청제술연합의체랍봉치료고혈압성뇌출혈적림상료효。방법검색Medline수거고、Embase수거고、Cochrane도서관、중국생물의학문헌수거고、만방수거고、유보자신망、중국기간전문수거고，수집소유로내혈종미창청제술연합의체랍봉치료고혈압성뇌출혈적림상수궤대조시험（ RCT），대부합납입표준적림상연구진행Meta분석。결과공납입9개수궤대조시험，Meta분석결과현시，로내혈종미창청제술연합의체랍봉조치료고혈압성뇌출혈총유효솔고우미창치료조（P＜0．05），사망솔저우미창치료조（P＜0．05）。결론로내혈종미창청제술연합의체랍봉치료고혈압성뇌출혈능제고료효，강저환자사망솔급제고생존질량。
Objective To observe the effect of minimally invasive hematoma evacuation combined with Edaravone therapy for hypertensive intracerebral hemorrhage .Methods A search was performed in databases of Medline , EMbase, Cochrane Library,CBM,Wanfang,Weipu,and CNKI Database.A data of randomized control tests(RCTs) on the treatment of hypertensive intracerebral hemorrhage with minimally invasive hematoma evacuation plus Edaravone therapy were obtained.A Meta-analysis on the studies in accordance with inclusion criteria was conducted .Results Nine RCTs on the topic were evaluated .The result of Meta-analysis showed that the total effective rate of the combined therapy group of minimally invasive hematoma evacuation and Edaravone was higher than that of the minimally invasive surgery group ( P<0 .05 ) ,and the mortality was lower than that of the minimally invasive surgery group ( P<0 .05 ) .Conclusion The combined therapy of minimally invasive hematoma evacuation and Edaravone can improve the patients′curative effect and daily living as well as reduce mortality .