CAJ | 학술논문

染料木素是从大豆、三叶草、葛根等植物中提取出来的异黄酮化合物，为植物雌激素的一种。其化学结构与内源性雌激素相似，能与雌激素胞膜及胞内受体结合发挥作用，如抗肿瘤、神经保护、调节骨代谢与脂代谢、抗肝纤维化、心血管保护及抗氧化等作用。本文主要综述近年来染料木素在抗心律失常、心肌保护、抗动脉粥样硬化等方面的作用及相关机制研究进展。
염료목소시종대두、삼협초、갈근등식물중제취출래적이황동화합물，위식물자격소적일충。기화학결구여내원성자격소상사，능여자격소포막급포내수체결합발휘작용，여항종류、신경보호、조절골대사여지대사、항간섬유화、심혈관보호급항양화등작용。본문주요종술근년래염료목소재항심률실상、심기보호、항동맥죽양경화등방면적작용급상관궤제연구진전。
Genistein is one of phytoestrogen extracted from soybean,shamrock and radix puerariae. Its chemical structure is similar to endogenous estrogen. And genistein can combine with membrane and endocellular estrogen receptor in anti-tumour,neuroprotection,bone and lipid metabolism regulation,hepatic fibrosis prevention,cardiovascular protection,an-tioxdation,etc. This study reviews the cardiovascular protection effects and mechanisms of Genistein,including antiarrhyth-mic,myocardial protection,antiatherosclerosis.