大连医科大学学报
大連醫科大學學報
대련의과대학학보
JOURNAL OF DALIAN MEDICAL UNIVERSITY
2014年
4期
400-404
,共5页
焦虑障碍%药物治疗%进展
焦慮障礙%藥物治療%進展
초필장애%약물치료%진전
anxiety disorder%drug treatment%progress
目前对焦虑障碍缺乏统一的诊断标准,国内外指南的分型和治疗用药不尽相同。一般认为焦虑障碍的一线用药为SSRIs、SNRIs,部分指南推荐普瑞巴林可以作为一线药物,难治性焦虑障碍可在抗抑郁药基础上加二线药物,或者非经典抗精神病药物、抗抽搐药物等,常规治疗时间一般在12~18个月,对于广泛性焦虑障碍( gen eral-ized anxiety disorder ,GAD)甚至需要终身治疗。
目前對焦慮障礙缺乏統一的診斷標準,國內外指南的分型和治療用藥不儘相同。一般認為焦慮障礙的一線用藥為SSRIs、SNRIs,部分指南推薦普瑞巴林可以作為一線藥物,難治性焦慮障礙可在抗抑鬱藥基礎上加二線藥物,或者非經典抗精神病藥物、抗抽搐藥物等,常規治療時間一般在12~18箇月,對于廣汎性焦慮障礙( gen eral-ized anxiety disorder ,GAD)甚至需要終身治療。
목전대초필장애결핍통일적진단표준,국내외지남적분형화치료용약불진상동。일반인위초필장애적일선용약위SSRIs、SNRIs,부분지남추천보서파림가이작위일선약물,난치성초필장애가재항억욱약기출상가이선약물,혹자비경전항정신병약물、항추휵약물등,상규치료시간일반재12~18개월,대우엄범성초필장애( gen eral-ized anxiety disorder ,GAD)심지수요종신치료。
Due to lack of uniform diagnostic criteria , the domestic and international cclassification and treatment guide-lines of anxiety disorders vary a lot currently .It is generally recognized that SSRIs and SNRIs are the first -line treatment of anxiety disorders.In addition, a minority of guidelines recommend pregabalin as the first -line drug.Refractory anxiety disorders can be treated by a combination of antidepressants with second -line drugs, non -classical antipsychotics or anti-convulsive drugs.Conventional treatment cycles are generally between 12 to 18 months.Lifelong treatment may be e-ven necessary for GAD .