CAJ | 학술논문

目的：评价阿立哌唑口崩片的有效性，为其有效使用提供借鉴。方法检索CBM、CKNI数据库，时间不限。纳入随机、半随机及临床对照试验。按Cochrane 5．0版质量评价标准评价研究质量和提取数据进行Meta分析。结果共纳入7个研究。 Meta分析显示：阿立哌唑口崩片与其他非经典抗精神病药物间疗效的差异无显著性意义[RR＝1．01，95％CI（0．93，1．10），P＝0．77]；阿立哌唑口崩片与经典抗精神病药物间疗效的差异无显著性意义[RR＝1．02，95％CI（0．95，1．09），P＝0．68]。结论阿立哌唑口崩片对精神分裂症的阳性、阴性症状均有明显疗效，且副作用低，值得推广。
목적：평개아립고서구붕편적유효성，위기유효사용제공차감。방법검색CBM、CKNI수거고，시간불한。납입수궤、반수궤급림상대조시험。안Cochrane 5．0판질량평개표준평개연구질량화제취수거진행Meta분석。결과공납입7개연구。 Meta분석현시：아립고서구붕편여기타비경전항정신병약물간료효적차이무현저성의의[RR＝1．01，95％CI（0．93，1．10），P＝0．77]；아립고서구붕편여경전항정신병약물간료효적차이무현저성의의[RR＝1．02，95％CI（0．95，1．09），P＝0．68]。결론아립고서구붕편대정신분렬증적양성、음성증상균유명현료효，차부작용저，치득추엄。
Objective To systematicly evaluate the efficacy of Brisking treating Schizophrenia , providing reference for the reasonable use of this drug .Methods We searched CBM , CNKI for randomized controlled trials ( RCTs) and quasi-ran-domization controlled trials .Quality assessment and data extraction were conducted by two reviewers independently .Meta-analyses were conducted with the Cochrane Collaboration ’ s RevMan 5.0 software.Results Seven trials met the inclusion criteria.Results Showed:The effects for Schizophrenia are no significant difference between brisking and other non -clas-sical antipsychotics[RR=1.01,95%CI(0.93,1.10),P=0.77].The effects for Schizophrenia are also no significant difference between Brisking and classical -antipsychotics [RR=1.02,95%CI(0.95,1.09),P=0.68].Conclusion No significant differences were observed in the effects between brisking and other antipsychotics for Schizophrenia , We could expand its use ,especially for incipient patients and elderly patients .