中国病理生理杂志
中國病理生理雜誌
중국병리생리잡지
CHINESE JOURNAL OF PATHOPHYSIOLOGY
2014年
7期
1218-1222,1227
,共6页
郭晓令%刘庆%王婵%郭永龙%余榕捷%陈建苏
郭曉令%劉慶%王嬋%郭永龍%餘榕捷%陳建囌
곽효령%류경%왕선%곽영룡%여용첩%진건소
诱导多能性干细胞%安全性%有效性
誘導多能性榦細胞%安全性%有效性
유도다능성간세포%안전성%유효성
Induced pluripotent stem cells%Safety%Efficiency
Induced pluripotent stem cells ( iPSCs) have been first induced from mouse fibroblasts since 2006, and the research on iPSCs has made great progress in the following years .iPS cell lines were established from different so-matic cells through DNA , RNA, protein, and small molecule compounds and various methods of transduction , making the induction of iPSCs more secure and effective , and more attractive prospect of clinical application .In this review , different somatic cell reprogramming , different levels of reprogramming , different transduction pathways , and prospect of application are discussed .
