CAJ | 학술논문

选择复方谷氨酰胺作为模型药物，填充于海藻植物胶囊壳中，测定其在体外释放度。结果表明，在模拟胃环境中复方谷氨酰胺2 h无药物释放；在模拟肠环境中35 min时，复方谷氨酰胺累计释放度已达标示量的70％；在60 min时，累计释放度达92%，符合药典规定。
선택복방곡안선알작위모형약물，전충우해조식물효낭각중，측정기재체외석방도。결과표명，재모의위배경중복방곡안선알2 h무약물석방；재모의장배경중35 min시，복방곡안선알루계석방도이체표시량적70％；재60 min시，루계석방도체92%，부합약전규정。
The compound glutamine is chosen as a model drug and packed into the seaweed plant capsule shells. The in vitro drug release of capsules is determined. The results show that the drug release of compound glutamine seaweed plant capsule is 0 after 2 hours in a simulated gastric environment and the drug release has reached 70% at 35 min and 92% at 60 min in simulated intestinal environment,can meet the pharmacopoeia standards.