中国临床保健杂志
中國臨床保健雜誌
중국림상보건잡지
CHINESE JOURNAL OF CLINICAL HEALTHCARE
2014年
4期
337-340
,共4页
武云涛%张薇%夏长泉%田国祥%王晓兵%李响%郝万峰%张晓冬%张峰%宋慧敏%孙艳明%朱润秀%高迎春
武雲濤%張薇%夏長泉%田國祥%王曉兵%李響%郝萬峰%張曉鼕%張峰%宋慧敏%孫豔明%硃潤秀%高迎春
무운도%장미%하장천%전국상%왕효병%리향%학만봉%장효동%장봉%송혜민%손염명%주윤수%고영춘
药物洗脱支架%冠状血管%西罗莫司%年龄因素%随访研究
藥物洗脫支架%冠狀血管%西囉莫司%年齡因素%隨訪研究
약물세탈지가%관상혈관%서라막사%년령인소%수방연구
Drug-eluting stents%Coronary vessels%Sirolimus%Age factors%Follow-up studies
目的：评价年龄因素对选择性冠状动脉内置入雷帕霉素洗脱支架（ DES ）的远期疗效的影响。方法对成功置入DES的316例男性冠心病患者进行随访调查，根据年龄分组：＞80～90岁组（82例）、＞70～80岁组（80例）、＞60～70岁组（92例）、＞45～60岁组（62例）。比较4组的随访结果，随访包括心绞痛复发、死亡、心肌梗死、卒中和再次血运重建的主要不良心脑血管事件。结果4组支架术成功率均为100％，随访率100％，随访5年，4组术后并发症发生率、卒中发生率差异无统计学意义（均P＞0．05）。再次血运重建率（10．9％、13．4％、19．6％、22．6％）和心绞痛复发率（15．9％、20％、32．6％、40．3％）＞80～90岁、＞70～80岁组低于＞60～70岁组、＞45～60岁组（ P＜0．05），全因病死率＞80～90岁组、＞70～80岁组高于＞60～70岁组、＞45～60岁组（7．3％、6．3％、2．2％、1．6％，P＜0．05），但心源性病死率差异无统计学意义。结论年龄因素对冠脉内支架术的疗效及安全性无明显影响。
目的：評價年齡因素對選擇性冠狀動脈內置入雷帕黴素洗脫支架（ DES ）的遠期療效的影響。方法對成功置入DES的316例男性冠心病患者進行隨訪調查，根據年齡分組：＞80～90歲組（82例）、＞70～80歲組（80例）、＞60～70歲組（92例）、＞45～60歲組（62例）。比較4組的隨訪結果，隨訪包括心絞痛複髮、死亡、心肌梗死、卒中和再次血運重建的主要不良心腦血管事件。結果4組支架術成功率均為100％，隨訪率100％，隨訪5年，4組術後併髮癥髮生率、卒中髮生率差異無統計學意義（均P＞0．05）。再次血運重建率（10．9％、13．4％、19．6％、22．6％）和心絞痛複髮率（15．9％、20％、32．6％、40．3％）＞80～90歲、＞70～80歲組低于＞60～70歲組、＞45～60歲組（ P＜0．05），全因病死率＞80～90歲組、＞70～80歲組高于＞60～70歲組、＞45～60歲組（7．3％、6．3％、2．2％、1．6％，P＜0．05），但心源性病死率差異無統計學意義。結論年齡因素對冠脈內支架術的療效及安全性無明顯影響。
목적：평개년령인소대선택성관상동맥내치입뢰파매소세탈지가（ DES ）적원기료효적영향。방법대성공치입DES적316례남성관심병환자진행수방조사，근거년령분조：＞80～90세조（82례）、＞70～80세조（80례）、＞60～70세조（92례）、＞45～60세조（62례）。비교4조적수방결과，수방포괄심교통복발、사망、심기경사、졸중화재차혈운중건적주요불양심뇌혈관사건。결과4조지가술성공솔균위100％，수방솔100％，수방5년，4조술후병발증발생솔、졸중발생솔차이무통계학의의（균P＞0．05）。재차혈운중건솔（10．9％、13．4％、19．6％、22．6％）화심교통복발솔（15．9％、20％、32．6％、40．3％）＞80～90세、＞70～80세조저우＞60～70세조、＞45～60세조（ P＜0．05），전인병사솔＞80～90세조、＞70～80세조고우＞60～70세조、＞45～60세조（7．3％、6．3％、2．2％、1．6％，P＜0．05），단심원성병사솔차이무통계학의의。결론년령인소대관맥내지가술적료효급안전성무명현영향。
Objective To assess the age factor on the long-term clinical outcomes in patients with coronary artery disease after the application of drug eluting stent ( DES) .Method A total of 316 patients with coronary artery disease,who underwent DES implantation in a single center from January 2004 toJanuary 2008 were included and di-vided into four groups:groupⅠ( patients aged 80-89 years old,n=82),groupⅡ(patients aged 70-79 years old, n=80).groupⅢ(patients aged 60-69 years old,n=92),and groupⅣ( patients with 40-59 years old,n=62). The long-term outcomes were compared among the four groups .The five years follow-up clinical end points of death , myocardial infarction ,stroke and any repeat revascularization were collected mainly by telephone interview after dis -charge retrospectively .Results Procedural success rates were 100%in the 4 groups.After the 5 years 100%follow-up,there were no significant differences in the incidence of complications ,and non-fatal stroke (P>0.05).The rates of reascularization (15.9%vs 20%vs 32.6% vs 40.3%) and recurrent angina (10.9% vs 13.4% vs 19.6% vs 22.6%) were were significantly lower in group ⅠandⅡ than that in groupⅢ and=Ⅳ,respectively (P <0.05). The all-cause mortality was higher in group I(7.3%)and Ⅱ(6.3%)than that in groupⅢ(2.2%) andⅣ(1.6%) (P <0.05).There were no was no significant differences in the cardiac mortality among four groups .Conclusion There is no significant influence of age factor on the prognosis and safety after the elective coronary stenting .
