中西医结合心血管病电子杂志
中西醫結閤心血管病電子雜誌
중서의결합심혈관병전자잡지
Cardiovascular Disease Journal of Integrated Traditional Chinese and Western Medicine (Electronic)
2014年
5期
52-52,55
,共2页
经颅磁刺激%酒依赖%抑郁
經顱磁刺激%酒依賴%抑鬱
경로자자격%주의뢰%억욱
rTMS%Alcohol dependence%Depression
目的：探讨重复经颅磁刺激（rTMS）对酒依赖患者伴发抑郁的快速起效作用。方法酒依赖伴抑郁患者60例，随机分为研究组（rTMS合并帕罗西汀组）和对照组（帕罗西汀组）各30例，治疗前及治疗后1、2、4周末应用汉密顿抑郁量表（HAMD）评定。结果治疗组有效率明显高于对照组，两组比较均有显著差异（P＜0．05）。两组HAMD评分均显著低于治疗前（P＜0．01），研究组HAMD评分较对照组下降更显著（P＜0．01）。结论经颅磁刺激结合抗抑郁药物治疗较单用抗抑郁药物治疗能更快更好的缓解酒依赖患者伴发的抑郁症状。
目的：探討重複經顱磁刺激（rTMS）對酒依賴患者伴髮抑鬱的快速起效作用。方法酒依賴伴抑鬱患者60例，隨機分為研究組（rTMS閤併帕囉西汀組）和對照組（帕囉西汀組）各30例，治療前及治療後1、2、4週末應用漢密頓抑鬱量錶（HAMD）評定。結果治療組有效率明顯高于對照組，兩組比較均有顯著差異（P＜0．05）。兩組HAMD評分均顯著低于治療前（P＜0．01），研究組HAMD評分較對照組下降更顯著（P＜0．01）。結論經顱磁刺激結閤抗抑鬱藥物治療較單用抗抑鬱藥物治療能更快更好的緩解酒依賴患者伴髮的抑鬱癥狀。
목적：탐토중복경로자자격（rTMS）대주의뢰환자반발억욱적쾌속기효작용。방법주의뢰반억욱환자60례，수궤분위연구조（rTMS합병파라서정조）화대조조（파라서정조）각30례，치료전급치료후1、2、4주말응용한밀돈억욱량표（HAMD）평정。결과치료조유효솔명현고우대조조，량조비교균유현저차이（P＜0．05）。량조HAMD평분균현저저우치료전（P＜0．01），연구조HAMD평분교대조조하강경현저（P＜0．01）。결론경로자자격결합항억욱약물치료교단용항억욱약물치료능경쾌경호적완해주의뢰환자반발적억욱증상。
Objective To explore the rapid effect of repetitive transcranial maignetic stimulation (rTMS)for alcohol dependence pa-tients with depressive symptoms.Methods 60 patients of alcohol dependence with depressive symptoms were randomly divided into study group (30 cases treated with rTMS plus paroxetine)and control group (30 cases treated with paroxetine ).The curative effect was assessed by using Hamilton Depression Scale (HAMD)at baseline and at the 1st,2nd,4th weekend of the treatment.Results The effective rate of the treatment group was significantly higher than the control group,there were significant differences between the two groups (P<0.05);Scores of HAMD in both groups decreased significantly compared with the baseline (P<0.01),the decrease of score of HAMD in study group was more obvious than that in control group (P<0.01).Conclusion rTMS in conjunction with antidrpressants have more rapid and good effect than single antidrpressants for patients of alcohol dependence with depressive symptoms.
