CAJ | 학술논문

目的：观察乔本甲状腺炎合并甲状腺乳头状癌的临床病理特征。方法分析我院16例乔本甲状腺炎合并甲状腺乳头状癌患者，通过巨检、HE染色和免疫细胞化学染色的方法对其临床病理特点进行分析。结果巨检标本呈灰白色结节样形状，表面光滑；镜下表现为乔本甲状腺炎与甲状腺乳头状癌混合病灶；免疫细胞化学染色发现抗体CK19（＋）的患者是16例，呈弥漫强阳性表达；抗体p53（＋）的患者有7例，呈弱阳性表达。结论了解乔本甲状腺炎合并甲状腺乳头状癌的病理特点，能够及早发现疑似患者，有利于改善临床预后。
목적：관찰교본갑상선염합병갑상선유두상암적림상병리특정。방법분석아원16례교본갑상선염합병갑상선유두상암환자，통과거검、HE염색화면역세포화학염색적방법대기림상병리특점진행분석。결과거검표본정회백색결절양형상，표면광활；경하표현위교본갑상선염여갑상선유두상암혼합병조；면역세포화학염색발현항체CK19（＋）적환자시16례，정미만강양성표체；항체p53（＋）적환자유7례，정약양성표체。결론료해교본갑상선염합병갑상선유두상암적병리특점，능구급조발현의사환자，유리우개선림상예후。
Objective To investigate the clinical and pathological features of Hashimoto's thyroiditis with thyroid papillary carcino-ma.Methods Retrospective analysis 16 casesHashimoto's thyroiditis with thyroid papillary carcinoma patients,by means ofmacroexamina-tion,HE staining and immunohistochemical staining was applied to analyze the clinical and pathological features.Results the giant speci-mens palenodular shape,smooth surface;endoscopic Hashimoto thyroiditis and thyroid papillary carcinoma mixed lesions;immunocytochemi-cal staining indicated that antibody CK19(+)were 16 cases,diffuse strong positive expression;antibody P53 (+)patients with 7 cases, were weak positive expression.Conclusion understanding pathological features of Hashimoto's thyroiditis with thyroid papillary carcinoma, early detection of the suspected patients,improve clinical prognosis.