中国医学前沿杂志（电子版）
中國醫學前沿雜誌（電子版）
중국의학전연잡지（전자판）
CHINESE JOURNAL OF THE FRONTIERS OF MEDICAL SCIENCE(ELECTRONIC VERSION)
2014年
7期
109-111
,共3页
高血压%脑出血%尼莫地平%奥拉西坦
高血壓%腦齣血%尼莫地平%奧拉西坦
고혈압%뇌출혈%니막지평%오랍서탄
Hypertensive%Cerebral hemorrhage%Nimodipine%Oxiracetam
目的：观察尼莫地平联合奥拉西坦治疗高血压脑出血患者认知功能恢复的临床疗效。方法将66例高血压脑出血患者随机分为试验组和对照组，对照组患者给予常规基础治疗，试验组患者在对照组基础上给予尼莫地平联合奥拉西坦治疗。治疗前、后进行CT扫描测定血肿和水肿体积，应用美国国立卫生研究院卒中量表（NIHSS）、简易精神状态表（MMES）、巴氏指数评分（BI）评价临床疗效。结果治疗后，两组患者血肿和水肿体积均减少，与治疗前比较差异有显著性（P＜0.05），且试验组与对照组比较差异有显著性（P＜0.05）；治疗后，两组患者NIHSS评分减少，MMES和BI评分升高，与治疗前比较差异有显著性（P＜0.05），且试验组与对照组比较差异有显著性（P＜0.05）。结论尼莫地平联合奥拉西坦治疗高血压脑出血效果显著，能有效减轻脑血肿和水肿状况，改善患者的神经功能和认知功能。
目的：觀察尼莫地平聯閤奧拉西坦治療高血壓腦齣血患者認知功能恢複的臨床療效。方法將66例高血壓腦齣血患者隨機分為試驗組和對照組，對照組患者給予常規基礎治療，試驗組患者在對照組基礎上給予尼莫地平聯閤奧拉西坦治療。治療前、後進行CT掃描測定血腫和水腫體積，應用美國國立衛生研究院卒中量錶（NIHSS）、簡易精神狀態錶（MMES）、巴氏指數評分（BI）評價臨床療效。結果治療後，兩組患者血腫和水腫體積均減少，與治療前比較差異有顯著性（P＜0.05），且試驗組與對照組比較差異有顯著性（P＜0.05）；治療後，兩組患者NIHSS評分減少，MMES和BI評分升高，與治療前比較差異有顯著性（P＜0.05），且試驗組與對照組比較差異有顯著性（P＜0.05）。結論尼莫地平聯閤奧拉西坦治療高血壓腦齣血效果顯著，能有效減輕腦血腫和水腫狀況，改善患者的神經功能和認知功能。
목적：관찰니막지평연합오랍서탄치료고혈압뇌출혈환자인지공능회복적림상료효。방법장66례고혈압뇌출혈환자수궤분위시험조화대조조，대조조환자급여상규기출치료，시험조환자재대조조기출상급여니막지평연합오랍서탄치료。치료전、후진행CT소묘측정혈종화수종체적，응용미국국립위생연구원졸중량표（NIHSS）、간역정신상태표（MMES）、파씨지수평분（BI）평개림상료효。결과치료후，량조환자혈종화수종체적균감소，여치료전비교차이유현저성（P＜0.05），차시험조여대조조비교차이유현저성（P＜0.05）；치료후，량조환자NIHSS평분감소，MMES화BI평분승고，여치료전비교차이유현저성（P＜0.05），차시험조여대조조비교차이유현저성（P＜0.05）。결론니막지평연합오랍서탄치료고혈압뇌출혈효과현저，능유효감경뇌혈종화수종상황，개선환자적신경공능화인지공능。
Objective To investigate the clinical effects of Nimodipine combined with Oxiracetam in patients with hypertensive cerebral hemorrhage. Method 66 cases of patients with hypertensive cerebral hemorrhage were randomly divided into treatment group and control group, the control group was given routine treatment and individual therapy, the treatment group was given Nimodipine combined with Oxiracetam treatment based on the control group. The volume of hematoma and perilesional edema of the two groups were determinated by using CT scan. The clinical effect was evaluated by the national institutes of health stroke scale (NIHSS) scores and the Barthel index (BI) scores and the mini mental state examination (MMES) scores before and after the treatment. Result After treatment, the volume of hematoma and perilesional edema of the two groups decreased signiifcantly, compared with pre-treatment the difference was signiifcant (P<0.05), and the treatment group compared with the control group the difference was signiifcant (P<0.05). The two groups included decreased NIHSS and elevated MMES and BI after treatment, compared with pre-treatment the difference was signiifcant (P<0.05), and the treatment group compared with the control group the difference was signiifcant (P<0.05). Conclusion Nimodipine combined with Oxiracetam is an effective treatment for hypertensive cerebral hemorrhage, can effectively reduced the size of edema zone around the hemotoma and improve the neurological function and cognitive function.
