CAJ | 학술논문

目的：探讨老年室性心律失常患者应用艾司洛尔联合胺碘酮的临床疗效。方法将135例室性心律失常老年患者随机均分为两组，均给予常规治疗，对照组患者在此基础上口服胺碘酮，观察组患者在对照组基础上静脉滴注艾司洛尔，比较两组的临床疗效。结果研究组疗效优于对照组，差异有显著性（Z＝-2.085，P＝0.037）；两组患者的不良反应主要包括头晕、恶心呕吐、低血压、心动过速、甲状腺功能异常。研究组患者不良反应率发生率为13.42%，对照组为14.70%，两组比较差异无显著性（χ2＝0.045，P＝0.832）。结论艾司洛尔与胺碘酮联合治疗老年室性心律失常的疗效优于单用胺碘酮，且不良反应小，临床具有重要参考价值。
목적：탐토노년실성심률실상환자응용애사락이연합알전동적림상료효。방법장135례실성심률실상노년환자수궤균분위량조，균급여상규치료，대조조환자재차기출상구복알전동，관찰조환자재대조조기출상정맥적주애사락이，비교량조적림상료효。결과연구조료효우우대조조，차이유현저성（Z＝-2.085，P＝0.037）；량조환자적불량반응주요포괄두훈、악심구토、저혈압、심동과속、갑상선공능이상。연구조환자불량반응솔발생솔위13.42%，대조조위14.70%，량조비교차이무현저성（χ2＝0.045，P＝0.832）。결론애사락이여알전동연합치료노년실성심률실상적료효우우단용알전동，차불량반응소，림상구유중요삼고개치。
Objective To study the Esmolol ventricular arrhythmia in elderly patients, the clinical curative effect of amiodarone combined treatment. Method 135 cases of ventricular arrhythmias were elderly patients were randomly divided into two groups, two groups were performed routine therapy and control group on the basis of oral amiodarone, observation group in the control group on the basis of intravenous drip Esmolol, compare the clinical curative effect of two groups. Result Two groups of clinical curative effect comparison, the difference was statistically signiifcant (Z=-2.085, P=0.037), the team curative effect was better than the control group;two group of adverse reactions mainly include dizziness, nausea, vomiting, hypotension, tachycardia, abnormal thyroid function, the team adverse reaction rate was 13.42% and 14.70% in control group, there was no statistically signiifcant difference in the two groups (χ2=0.045, P=0.832). Conclusion Esmolol with amiodarone combined treatment of ventricular arrhythmia in elderly patients with curative effect is better than that of amiodarone alone, and the characteristics of adverse reactions to small clinical has important reference value.