CAJ | 학술논문

高脂血症是血管及脏器疾病的主要基础病变之一，中医药在防治高脂血症方面具有毒副作用小，疗效明显的优势，建立高脂血症诊断辅助平台有助于提高诊疗效率，并为高脂血症辨证分型标准化研究提供数据采集、存储与分析的平台。首先建立高脂血症四诊信息临床采集平台及数据库，记录患者就诊不同时期的望诊图像及其余三诊的文字信息，方便医师更准确地掌握治疗过程中患者的临床表现，从而总结治疗经验，提高治疗效果；在此基础上利用可调整相似度阈值的自适应聚类算法对已采集的897个病例四诊信息进行分类，最终得到5类，将得到的每个类别中所对应样本的病症特征与所属中医的证候类别联系起来，最后用相似性算法判断新采集病例属于的哪一类，为中医辨证分型诊断提供建议。
고지혈증시혈관급장기질병적주요기출병변지일，중의약재방치고지혈증방면구유독부작용소，료효명현적우세，건립고지혈증진단보조평태유조우제고진료효솔，병위고지혈증변증분형표준화연구제공수거채집、존저여분석적평태。수선건립고지혈증사진신식림상채집평태급수거고，기록환자취진불동시기적망진도상급기여삼진적문자신식，방편의사경준학지장악치료과정중환자적림상표현，종이총결치료경험，제고치료효과；재차기출상이용가조정상사도역치적자괄응취류산법대이채집적897개병례사진신식진행분류，최종득도5류，장득도적매개유별중소대응양본적병증특정여소속중의적증후유별련계기래，최후용상사성산법판단신채집병례속우적나일류，위중의변증분형진단제공건의。
Hyperlipidemia is one of the main basic lesions of blood vessels and organ diseases. Traditional Chinese medicine (TCM) has been used in the prevention and treatment of hyperlipidemia with advantages such as little drug side effects and obvious efficacy. The establishment of hyperlipidemia diagnostic aid platform helped to improve treatment efficiency, and provide a platform for data acquisition, storage and analysis for research on hyperlipidemia syndrome standardization. At first, a collection system was implemented, which was consisted of tongue image and the text information of the other three diagnostic methods, for doctor's accurate mastering of patient's clinical manifesta-tions and improvement of therapeutic effect. Through this platform, a clustering algorithm was applied to analyze clin-ical information of four diagnostic methods among 897 hyperlipemia cases, which had been classified into 5 cate-gories. Compare disease characteristics of samples in every category with syndromes category and find out the rela-tionships between them, by which the foundation of hyperlipemia syndrome differentiation standardization will be es-tablish. It provided suggestions on TCM syndrome differentiation and diagnosis.