中国医院用药评价与分析
中國醫院用藥評價與分析
중국의원용약평개여분석
EVALUATION AND ANAL YSIS OF DRUG-USE IN HOSPITALS OF CHINA
2014年
8期
763-764,765
,共3页
大肠埃希菌%抗菌药物%耐药率
大腸埃希菌%抗菌藥物%耐藥率
대장애희균%항균약물%내약솔
Escherichia coli%Antibiotics%Drug resistance rate
目的：分析2009-2013年我院大肠埃希菌的耐药情况，以指导临床合理用药，减少细菌耐药。方法：使用Excel统计、分析2009-2013年我院检验科分离的1518株大肠埃希菌对常用的22种抗菌药物的药敏试验数据。结果：大肠埃希菌的检出率逐年增高；除哌拉西林/他唑巴坦、头孢哌酮/舒巴坦、阿米卡星、磷霉素、呋喃妥因、美罗培南、亚胺培南外，其余15种抗菌药物均有较高的耐药率。结论：我院大肠埃希菌耐药形势严峻。减少侵入性操作、降低医院感染的发生率是减少大肠埃希菌耐药率的有效措施。建议加强医院感染科、药剂科、细菌室的相互合作，做好细菌耐药预警工作，协助临床医师合理选择、使用抗菌药物。
目的：分析2009-2013年我院大腸埃希菌的耐藥情況，以指導臨床閤理用藥，減少細菌耐藥。方法：使用Excel統計、分析2009-2013年我院檢驗科分離的1518株大腸埃希菌對常用的22種抗菌藥物的藥敏試驗數據。結果：大腸埃希菌的檢齣率逐年增高；除哌拉西林/他唑巴坦、頭孢哌酮/舒巴坦、阿米卡星、燐黴素、呋喃妥因、美囉培南、亞胺培南外，其餘15種抗菌藥物均有較高的耐藥率。結論：我院大腸埃希菌耐藥形勢嚴峻。減少侵入性操作、降低醫院感染的髮生率是減少大腸埃希菌耐藥率的有效措施。建議加彊醫院感染科、藥劑科、細菌室的相互閤作，做好細菌耐藥預警工作，協助臨床醫師閤理選擇、使用抗菌藥物。
목적：분석2009-2013년아원대장애희균적내약정황，이지도림상합리용약，감소세균내약。방법：사용Excel통계、분석2009-2013년아원검험과분리적1518주대장애희균대상용적22충항균약물적약민시험수거。결과：대장애희균적검출솔축년증고；제고랍서림/타서파탄、두포고동/서파탄、아미잡성、린매소、부남타인、미라배남、아알배남외，기여15충항균약물균유교고적내약솔。결론：아원대장애희균내약형세엄준。감소침입성조작、강저의원감염적발생솔시감소대장애희균내약솔적유효조시。건의가강의원감염과、약제과、세균실적상호합작，주호세균내약예경공작，협조림상의사합리선택、사용항균약물。
OBJECTIVE:To analyze the antimicrobial resistance of Escherichia coli in our hospital during 2009-2013 so as to guide clinical rational use of drugs and reduce bacterial resistance. METHODS:The susceptibility test results of 1 518 stains of Escherichia coli to 22 commonly-used antibiotics in our hospital during 2009-2013 were analyzed statistically using Excel. RE-SULTS:The detection rate of Escherichia coli increased year by year. Escherichia coli were highly resistant to 15 commonly-used an-tibiotics except piperacillin/tazobactam,cefoperazone/sulbactam,amikacin,fosfomycin,nitrofurantoin,meropenem and imipenem. CONCLUSIONS:The antimicrobial resistance of Escherichia coli in our hospital was serious. Reducing the chances of invasive op-eration and the incidence of hospital infection were the effective measures reducing antimicrobial resistance rate of Escherichia coli. It is advisable to strengthen cooperation among department of infection,department of pharmacy and microbiology laboratory,con-duct early warning for bacterial resistance and cooperate with clinicians to achieve rational choice and use of antibiotics.
