临床医药实践
臨床醫藥實踐
림상의약실천
PROCEEDING OF CLINICAL MEDICINE
2014年
8期
568-570
,共3页
肝病%血清%铁蛋白
肝病%血清%鐵蛋白
간병%혈청%철단백
hepaticdisease%serum%ferritin
目的：探讨肝病患者血清铁蛋白检测的临床诊断意义及在肝损伤过程中的作用。方法：选择2010年1月-2013年12月诊治的376例肝病患者（慢性肝炎147例，肝硬化133例，肝细胞癌96例）和90例健康体检者作为研究对象，采用化学发光法对各组血清铁蛋白检测并比较。结果：与健康者相比，肝病患者血清铁蛋白水平明显升高，差异有统计学意义（ P﹤0.05）；与慢性肝炎、肝硬化患者相比，肝细胞癌患者血清铁蛋白水平明显升高，差异有统计学意义（ P﹤0.05）。肝病患者血清铁蛋白水平与谷丙转氨酶（ ALT）、谷草转氨酶（ AST）呈正相关。结论：血清铁蛋白为肝病诊断提供参考依据，指导肝病的临床诊断和预后。
目的：探討肝病患者血清鐵蛋白檢測的臨床診斷意義及在肝損傷過程中的作用。方法：選擇2010年1月-2013年12月診治的376例肝病患者（慢性肝炎147例，肝硬化133例，肝細胞癌96例）和90例健康體檢者作為研究對象，採用化學髮光法對各組血清鐵蛋白檢測併比較。結果：與健康者相比，肝病患者血清鐵蛋白水平明顯升高，差異有統計學意義（ P﹤0.05）；與慢性肝炎、肝硬化患者相比，肝細胞癌患者血清鐵蛋白水平明顯升高，差異有統計學意義（ P﹤0.05）。肝病患者血清鐵蛋白水平與穀丙轉氨酶（ ALT）、穀草轉氨酶（ AST）呈正相關。結論：血清鐵蛋白為肝病診斷提供參攷依據，指導肝病的臨床診斷和預後。
목적：탐토간병환자혈청철단백검측적림상진단의의급재간손상과정중적작용。방법：선택2010년1월-2013년12월진치적376례간병환자（만성간염147례，간경화133례，간세포암96례）화90례건강체검자작위연구대상，채용화학발광법대각조혈청철단백검측병비교。결과：여건강자상비，간병환자혈청철단백수평명현승고，차이유통계학의의（ P﹤0.05）；여만성간염、간경화환자상비，간세포암환자혈청철단백수평명현승고，차이유통계학의의（ P﹤0.05）。간병환자혈청철단백수평여곡병전안매（ ALT）、곡초전안매（ AST）정정상관。결론：혈청철단백위간병진단제공삼고의거，지도간병적림상진단화예후。
Tostudytheclinicaldiagnosissignificanceofserumferritinforhepaticpatientsandtheroleduring the liver injury. Methods:The 376 cases of hepatic disease(147 cases of chronic hepatitis,133 cases of liver cirrhosis,96 cases of liver cell carcinoma)and 90 cases of health persons in hospital during the period from January 2010 to December 2013 were regarded as the research subjects. The serum ferritin levels in the subjects were determined and compared by chemilumines-cence methods. Results:Compared with the health persons,the serum ferritin levels were significantly increased in hepatic pa-tients with statistical difference(P﹤0. 05);compared with the chronic hepatitis and liver cirrhosis,the serum ferritin levels were significantly increased in patients of liver cell carcinoma with statistical difference(P﹤0. 05). The serum ferritin levels were positive correlated with alanine aminotransferase( ALT)and aspartate aminotransferase( AST)for patients with hepatic disease. Conclusion:The serum ferritin determination can provide the reference for the diagnosis of hepatic disease and guide the clinical diagnosis and prognosis for hepatic disease.
