山东医学高等专科学校学报
山東醫學高等專科學校學報
산동의학고등전과학교학보
JOURNAL OF SHANDONG MEDICAL COLLEGE
2014年
3期
237-239
,共3页
施保利通%婴儿%急性上呼吸道感染%疗效%安全性
施保利通%嬰兒%急性上呼吸道感染%療效%安全性
시보리통%영인%급성상호흡도감염%료효%안전성
Esberitox%Infant%Acute upper respir-atory tract infection%Curative effect%Safety
目的：探讨不同药物对婴儿急性上呼吸道感染的疗效和安全性。方法将360例年龄6～12个月的急性上呼吸道感染婴儿随机分为三组，观察组给予口服施保利通片，对照甲组给予口服利巴韦林颗粒，对照乙组给予口服儿童回春颗粒。三组均辅以小儿柴桂退热口服液和物理降温治疗。治疗后动态观察患儿每日体温高峰值，体温恢复正常时间，症状完全消失时间，皮疹发生情况，胃肠道反应，对外周血白细胞的影响以及肝肾功能损害情况。结果施保利通组72 h内每日体温高峰值较儿童回春组和利巴韦林组有明显下降，体温完全恢复正常的时间和症状完全消失的时间均明显缩短，具有统计学意义（ P ＜0．05）。5d后复查血常规，显示施保利通组白细胞总数均在正常范围；儿童回春组有15例白细胞降低，占该组总人数的12．5％，利巴韦林组有30例白细胞明显降低，占该组总人数的25％，具有统计学意义（ P ＜0．05）。结论施保利通治疗婴儿急性上呼吸道感染效果显著，副作用发生率低，安全性好。
目的：探討不同藥物對嬰兒急性上呼吸道感染的療效和安全性。方法將360例年齡6～12箇月的急性上呼吸道感染嬰兒隨機分為三組，觀察組給予口服施保利通片，對照甲組給予口服利巴韋林顆粒，對照乙組給予口服兒童迴春顆粒。三組均輔以小兒柴桂退熱口服液和物理降溫治療。治療後動態觀察患兒每日體溫高峰值，體溫恢複正常時間，癥狀完全消失時間，皮疹髮生情況，胃腸道反應，對外週血白細胞的影響以及肝腎功能損害情況。結果施保利通組72 h內每日體溫高峰值較兒童迴春組和利巴韋林組有明顯下降，體溫完全恢複正常的時間和癥狀完全消失的時間均明顯縮短，具有統計學意義（ P ＜0．05）。5d後複查血常規，顯示施保利通組白細胞總數均在正常範圍；兒童迴春組有15例白細胞降低，佔該組總人數的12．5％，利巴韋林組有30例白細胞明顯降低，佔該組總人數的25％，具有統計學意義（ P ＜0．05）。結論施保利通治療嬰兒急性上呼吸道感染效果顯著，副作用髮生率低，安全性好。
목적：탐토불동약물대영인급성상호흡도감염적료효화안전성。방법장360례년령6～12개월적급성상호흡도감염영인수궤분위삼조，관찰조급여구복시보리통편，대조갑조급여구복리파위림과립，대조을조급여구복인동회춘과립。삼조균보이소인시계퇴열구복액화물리강온치료。치료후동태관찰환인매일체온고봉치，체온회복정상시간，증상완전소실시간，피진발생정황，위장도반응，대외주혈백세포적영향이급간신공능손해정황。결과시보리통조72 h내매일체온고봉치교인동회춘조화리파위림조유명현하강，체온완전회복정상적시간화증상완전소실적시간균명현축단，구유통계학의의（ P ＜0．05）。5d후복사혈상규，현시시보리통조백세포총수균재정상범위；인동회춘조유15례백세포강저，점해조총인수적12．5％，리파위림조유30례백세포명현강저，점해조총인수적25％，구유통계학의의（ P ＜0．05）。결론시보리통치료영인급성상호흡도감염효과현저，부작용발생솔저，안전성호。
Objective To investigate the efficacy and safety of different drugs on infant acute upper re-spiratory tract infection .Methods 360 infants aged 6-12 months with acute upper respiratory tract infection were randomly divided into the observation group treated with Esberitox ,The contrast group A treated with ribavirin granules and the contrast group B treated with rejuvenation .All the three groups were sup-plemented by oral administration of cinnamomum wilsonii gamble and physical cooling treatment .Daily temperature peak value ,body temperature returning to normal ,complete resolution of symptoms ,occur-rence of rash ,gastrointestinal reaction ,the effect on peripheral w hite blood cells and liver and kidney dam-age were observed dynamically .Results The daily temperature peak value ,the time of body temperature re-turning to normal and the complete resolution of symptoms in the observation group decreased significantly more than the contrast group A and the contrast group B ( P <0 .05) .The routine blood test after 5 days of treatment showed that the total white blood cells were normal ,that the white blood cells decreased in 15 cases(12 . 5% ) in the contrast group A and that the white blood cells decreased in 30 cases(25% ) in the contrast group B( P<0 .05) .Conclusion Esberitox in treating infant acute upper respiratory tract infection can produce curative effect and good security with few side-effects .
