CAJ | 학술논문

对7例肺癌脑转移患者按照铅门宽度(1 cm，2.5 cm和5 cm)和螺距(0.15,0.30和0.45)的组合设计螺旋断层放疗计划，对其靶区、正常组织和治疗时间差异分析比较。所有计划均给予全脑CTV 30 Gy，转移灶GTV 50 Gy，计划分次为10次。结果证明靶区仅GTV的平均剂量和适形度(CI)差异有统计学意义(P =0.0021, P =0.0128)，危及器官均在正常剂量限制范围以内，治疗时间与铅门宽度近似成反比例，螺距对其影响较小。研究表明5 cm的铅门宽度能够有效缩短治疗时间、提高治疗效率。
대7례폐암뇌전이환자안조연문관도(1 cm，2.5 cm화5 cm)화라거(0.15,0.30화0.45)적조합설계라선단층방료계화，대기파구、정상조직화치료시간차이분석비교。소유계화균급여전뇌CTV 30 Gy，전이조GTV 50 Gy，계화분차위10차。결과증명파구부GTV적평균제량화괄형도(CI)차이유통계학의의(P =0.0021, P =0.0128)，위급기관균재정상제량한제범위이내，치료시간여연문관도근사성반비례，라거대기영향교소。연구표명5 cm적연문관도능구유효축단치료시간、제고치료효솔。
Tomotherapy plans were produced using a combination offi eld widths (1 cm, 2.5 cm and 5 cm) and pitches (0.15, 0.30, and 0.45) for seven patients with brain metastases from lung cancer, the plans were compared with dosimetric parameters, protection of organs at risk (OAR) dose and treatment times. Al plans were defi ned that CTV with 30Gy and GTV 50 Gy by ten fraction synchronously. The results showed that the mean dose andCI for GTV was statistical difference (P=0.002 1,P=0.012 8), OARs were within the normal range, the treatment time increased inversely proportional to the jaw width, but had lesser impact on the pitch.This study showed plans produced with 5 cm jaw was an effective method for patients with brain metastases from lung cancer.