CAJ | 학술논문

目的：探讨右美托咪啶预防腹腔镜术中寒颤的效果。方法80例行腹腔镜手术的患者随机分为A、B两组(各40例)，分别于静脉靶控输注麻醉后静脉泵入右美托咪啶(B组)及等体积生理盐水(A组)，采用Wrench分级评价术中寒颤发生率及程度，根据OAA/S评分标准评价手术期间镇痛效果，同时采用BCS评价术后3、6、12、24 h的舒适程度，记录整个手术过程的不良反应情况。结果 B组术中寒颤发生率低于A组(P<0.05)，且两组寒颤严重程度的差异有统计学意义(P<0.05)；B组的术中镇痛效果及舒适程度评分均优于A组，差异均有统计学意义(P<0.05)。两组不良反应的差异无统计学意义(P>0.05)。结论右美托咪啶预防腔镜麻醉术中寒颤的效果较好，并可提高镇痛效果及舒适度。
목적：탐토우미탁미정예방복강경술중한전적효과。방법80례행복강경수술적환자수궤분위A、B량조(각40례)，분별우정맥파공수주마취후정맥빙입우미탁미정(B조)급등체적생리염수(A조)，채용Wrench분급평개술중한전발생솔급정도，근거OAA/S평분표준평개수술기간진통효과，동시채용BCS평개술후3、6、12、24 h적서괄정도，기록정개수술과정적불량반응정황。결과 B조술중한전발생솔저우A조(P<0.05)，차량조한전엄중정도적차이유통계학의의(P<0.05)；B조적술중진통효과급서괄정도평분균우우A조，차이균유통계학의의(P<0.05)。량조불량반응적차이무통계학의의(P>0.05)。결론우미탁미정예방강경마취술중한전적효과교호，병가제고진통효과급서괄도。
Objective To explore the preventive effect of dexmedetomidine on intraoperative chills in laparoscopic surgery. Methods There were 80 patients underwent laparoscopic surgery from randomly assigned into group A and group B (n=40). After the target-controlled infusion-based anesthesia, group A received intravenous infusion of normal saline and group B received dexmedetomidine. The Wrench grading was used to evaluate the incidence and severity of intraoperative chills. The OAA/S scale was scored to evaluate the analgesic effect. The body condition score (BCS) was recorded at 3rd hour, 6th hour, 12th hour and 24th hour after operation. Meanwhile, the adverse reactions were recorded during the entire surgical procedure. Results The incidence of intraoperative chills in group B was lower than that of A group (P<0.05), and the difference of the severity of chills between the two groups had statistical significance (P<0.05). The intraoperative analgesia and comfort scores of group B were better than those of group A, and this difference was statistically significant (P<0.05). There was not statistical significance in the adverse reactions between both groups (P>0.05). Conclusion The preventive effect of dexmedetomidine on intraoperative chills of laparoscopic surgery is good and it can improve the analgesic effect and comfort level.