中国伤残医学
中國傷殘醫學
중국상잔의학
CHINESE JOURNAL OF TRAUMA AND DISABILITY MEDICINE
2014年
16期
12-13,14
,共3页
弥漫性脑胶质瘤%放射治疗%癫痫控制
瀰漫性腦膠質瘤%放射治療%癲癇控製
미만성뇌효질류%방사치료%전간공제
Diffuse gliomas%Radiotherapy%Seizure control
目的:探讨传统放射治疗对胶质瘤引起的癫痫的影响。方法:回顾性分析2005年后成人恶性脑胶质瘤合并有癫痫发作的患者45例,分析传统放射治疗后难治性癫痫的反应和预后。结果:放射治疗后3个月,71%患者(32/45)癫痫发作频率明显下降;76%II期脑胶质瘤(26/34)放射治疗后12个月后,癫痫发作频率明显下降。 MRI显示肿瘤缩小的患者癫痫发作频率大多降低,而MRI肿瘤体积变化不大的患者癫痫发作频率也显著地降低。结论:放射治疗弥漫性脑胶质瘤合并难治性癫痫有益于控制癫痫发作,疗效与MRI肿瘤缩小相关性不大。
目的:探討傳統放射治療對膠質瘤引起的癲癇的影響。方法:迴顧性分析2005年後成人噁性腦膠質瘤閤併有癲癇髮作的患者45例,分析傳統放射治療後難治性癲癇的反應和預後。結果:放射治療後3箇月,71%患者(32/45)癲癇髮作頻率明顯下降;76%II期腦膠質瘤(26/34)放射治療後12箇月後,癲癇髮作頻率明顯下降。 MRI顯示腫瘤縮小的患者癲癇髮作頻率大多降低,而MRI腫瘤體積變化不大的患者癲癇髮作頻率也顯著地降低。結論:放射治療瀰漫性腦膠質瘤閤併難治性癲癇有益于控製癲癇髮作,療效與MRI腫瘤縮小相關性不大。
목적:탐토전통방사치료대효질류인기적전간적영향。방법:회고성분석2005년후성인악성뇌효질류합병유전간발작적환자45례,분석전통방사치료후난치성전간적반응화예후。결과:방사치료후3개월,71%환자(32/45)전간발작빈솔명현하강;76%II기뇌효질류(26/34)방사치료후12개월후,전간발작빈솔명현하강。 MRI현시종류축소적환자전간발작빈솔대다강저,이MRI종류체적변화불대적환자전간발작빈솔야현저지강저。결론:방사치료미만성뇌효질류합병난치성전간유익우공제전간발작,료효여MRI종류축소상관성불대。
To expoler the effect of conventional radiotherapy on glioma related seizures .Methods:Seizure response and outcome following conventional radiotherapy in 45 patients with glioma were retrospectively analyzed .Results:At 3 months after radiothera-py, seizure reduction was significant in 32/45 patients and in 26/34 patients with grade II gliomas .Seizure reduction was observed more often among patients with an objective tumor response on MRI , but patients with no change on MRI also had a significant seizure reduc-tion.Conclusion:Conventional radiotherapy should be helpful to seizure reduction in patients with medically intractable epilepsy from dif -fuse gliomas, epilepsy control may not not strictly associated with tumor shrinkage as shown on MRI .