中国实用医药
中國實用醫藥
중국실용의약
CHINA PRACTICAL MEDICAL
2014年
19期
41-42
,共2页
杨蕾%张培荣%王宇航%刘晓宇%李兵%赵香梅%董淑娟%贺文奇%许文克%楚英杰
楊蕾%張培榮%王宇航%劉曉宇%李兵%趙香梅%董淑娟%賀文奇%許文剋%楚英傑
양뢰%장배영%왕우항%류효우%리병%조향매%동숙연%하문기%허문극%초영걸
肾素-血管紧张素系统抑制剂%尿微量白蛋白
腎素-血管緊張素繫統抑製劑%尿微量白蛋白
신소-혈관긴장소계통억제제%뇨미량백단백
Renin-angiotension system inhibitor%Microalbuminuria
目的：评价坎地沙坦酯联合培哚普利治疗高血压患者尿微量白蛋白的临床疗效。方法高血压患者150例临床资料进行分析，分别使用坎地沙坦酯8 mg/d(CA组)、培哚普利4 mg/d(PE组)、坎地沙坦酯8 mg/d联合培哚普利4 mg/d(CP组)，测定治疗前后的血压、尿微量白蛋白值。结果CP组、CA组、PE组的总有效率分别为90.00%、74.00%、72.00%， CP组疗效优于CA组和PE组，差异具有统计学意义(P<0.05)；三组方案都可以降低尿微量白蛋白含量， CP组能显著减低尿微量白蛋白含量，优于CA组及PE组，差异均具有统计学意义(P<0.05)。结论坎地沙坦酯与培哚普利联合治疗高血压患者尿微量白蛋白具有良好效果。
目的：評價坎地沙坦酯聯閤培哚普利治療高血壓患者尿微量白蛋白的臨床療效。方法高血壓患者150例臨床資料進行分析，分彆使用坎地沙坦酯8 mg/d(CA組)、培哚普利4 mg/d(PE組)、坎地沙坦酯8 mg/d聯閤培哚普利4 mg/d(CP組)，測定治療前後的血壓、尿微量白蛋白值。結果CP組、CA組、PE組的總有效率分彆為90.00%、74.00%、72.00%， CP組療效優于CA組和PE組，差異具有統計學意義(P<0.05)；三組方案都可以降低尿微量白蛋白含量， CP組能顯著減低尿微量白蛋白含量，優于CA組及PE組，差異均具有統計學意義(P<0.05)。結論坎地沙坦酯與培哚普利聯閤治療高血壓患者尿微量白蛋白具有良好效果。
목적：평개감지사탄지연합배타보리치료고혈압환자뇨미량백단백적림상료효。방법고혈압환자150례림상자료진행분석，분별사용감지사탄지8 mg/d(CA조)、배타보리4 mg/d(PE조)、감지사탄지8 mg/d연합배타보리4 mg/d(CP조)，측정치료전후적혈압、뇨미량백단백치。결과CP조、CA조、PE조적총유효솔분별위90.00%、74.00%、72.00%， CP조료효우우CA조화PE조，차이구유통계학의의(P<0.05)；삼조방안도가이강저뇨미량백단백함량， CP조능현저감저뇨미량백단백함량，우우CA조급PE조，차이균구유통계학의의(P<0.05)。결론감지사탄지여배타보리연합치료고혈압환자뇨미량백단백구유량호효과。
Objective To evaluate the clinical effect of candesartan cilexetil and perindopril on urinary microalbumin in hypertension patients.MethodsThere were 150 patients with hypertension included in the study, 50 cases for each group: candesartan cilexetil 8 mg/d (groupCA), perindopril 4 mg/d (group PE), candesartan cilexetil 8 mg/d combined with perindopril 4 mg/d (CP group), blood pressure, urinary albumin were analyzed. ResultsGroup CP , group CA, group PE, the total effective rate was 90%, 74%, 72%.The CP group was better than group CA, group PE , there were statistically significant (P<0.05); three groups could reduce urinary albumin content; group CP reduced the urinary albumin significantly, which was better than that of group CA and group PE, there were statistically significant (P<0.05).ConclusionCandesartan cilexetil combined with perindopril can treat microalbuminuria for patients with hypertension effectively.
