CAJ | 학술논문

目的：探讨西黄胶囊对乳腺癌术后放疗患者免疫功能及生活质量的影响。方法乳腺癌术后患者43例，随机分治疗组(22例)及对照组(21例)。对照组接受单纯放疗，治疗组在对照组基础上，加用西黄胶囊治疗。在治疗前及治疗后检测两组患者血清T细胞亚群水平，并比较治疗前后KPS评分。结果治疗组治疗后的CD3、CD4和CD4/CD8指标较治疗前均有提高(P<0.05)，与对照组治疗后比较，差异有统计学意义(P<0.05)；治疗组治疗后KPS评分明显上升，与对照组比较，差异有统计学意义(P<0.05)。结论西黄胶囊可以明显提高乳腺癌术后放疗患者的免疫功能水平，改善放疗期间的生存质量。
목적：탐토서황효낭대유선암술후방료환자면역공능급생활질량적영향。방법유선암술후환자43례，수궤분치료조(22례)급대조조(21례)。대조조접수단순방료，치료조재대조조기출상，가용서황효낭치료。재치료전급치료후검측량조환자혈청T세포아군수평，병비교치료전후KPS평분。결과치료조치료후적CD3、CD4화CD4/CD8지표교치료전균유제고(P<0.05)，여대조조치료후비교，차이유통계학의의(P<0.05)；치료조치료후KPS평분명현상승，여대조조비교，차이유통계학의의(P<0.05)。결론서황효낭가이명현제고유선암술후방료환자적면역공능수평，개선방료기간적생존질량。
Objective To study the clinical effect of Xihuang capsules on immune function of patients with breast cancer receiving postoperative radiotherapy.MethodsDivided 43 patients with breast cancer into two groups: treatment group(n=22) was treated with Xihuang capsules and radiotherapy; control group(n=21) was treated with radiotherapy only. Then T-lymphocyte subsets Resultsand Karnofsky(KPS) scores were compared before and after treatment in the two groups.ResultsThe level of CD3, CD4 and CD4/CD8 in treatment group were improved significantly than those in control group(P<0.05) ; the KPS scores increased more significantly in the treatment group than those in control group (P<0.05).ConclusionXihuang capsules can improve the immune function and life quality of patients with breast caner receiving postoperative radiotherapy.