CAJ | 학술논문

目的：探讨分析婴幼儿巨细胞病毒(CMV)肺炎的临床特点和诊治方法。方法36例感染巨细胞病毒的患儿随机数字表法分成两组，治疗组18例在常规治疗基础上采用更昔洛韦和丙种球蛋白治疗，对照组仅采用更昔洛韦治疗，对比其临床疗效。结果所有患儿临床主要表现为咳嗽、咳痰、发热，部分有气喘、腹泻、口吐泡沫等情况出现，经检测，血清CMV-IgM抗体和CMV-DNA检查均阳性32例；合并肺炎支原体感染5例；伴心肌损害14例。治疗后，治疗组总有效率为100.00%，对照组总有效率为94.44%，差异具有统计学意义(P<0.05)。结论结合多种实验室诊断方法可提高CMV肺炎的诊断，做到尽早治疗。
목적：탐토분석영유인거세포병독(CMV)폐염적림상특점화진치방법。방법36례감염거세포병독적환인수궤수자표법분성량조，치료조18례재상규치료기출상채용경석락위화병충구단백치료，대조조부채용경석락위치료，대비기림상료효。결과소유환인림상주요표현위해수、해담、발열，부분유기천、복사、구토포말등정황출현，경검측，혈청CMV-IgM항체화CMV-DNA검사균양성32례；합병폐염지원체감염5례；반심기손해14례。치료후，치료조총유효솔위100.00%，대조조총유효솔위94.44%，차이구유통계학의의(P<0.05)。결론결합다충실험실진단방법가제고CMV폐염적진단，주도진조치료。
ObjectiveTo analyze clinical feature and treatment Methods of cytomegalovirus pneumonia in infants.MethodsRetrospectively analyzed clinical data of 36 cases of infants with cytomegalovirus pneumonia. They were divided into two groups based on random number table method. The treatment group used ganciclovir and gamma globulin. The control group used ganciclovir only, and then compared their clinical effect. ResultsThe main clinical manifestations were cough, sputum, fever, some had asthma, diarrhea, vomit foam, after testing, serum CMV-IgM antibodies and CMV-DNA were positive for 32 cases; 5 cases with combined mycoplasma pneumoniae infection; 14 cases with myocardial damages. After treatment, the total effective rate of treatment group was 100%, control group was 94.44%, difference was statistically significant between two groups(P<0.05).ConclusionCombined with various laboratory diagnostic methods can improve the diagnosis of CMV pneumonia.