医学信息
醫學信息
의학신식
MEDICAL INFORMATION
2014年
21期
645-645
,共1页
苯扎贝特%横纹肌溶解症
苯扎貝特%橫紋肌溶解癥
분찰패특%횡문기용해증
Bzafibrate%Rhabdomyolysis
苯扎贝特可能引起肌炎、肌病和横纹肌溶解症,尽管发生率低,但在应用中也应注意肌酶、肝酶、肾功的监测和患者症状变化,服用前详细告知患者该药的不良反应,以便急时发现;该患者出现症状后急时停用,并查了肌酶、肝酶和肾功结合症状证实了横纹肌溶解症,分析可能的原因除患者肾功轻度降低、贫血等体质原因,首先应了解肝肾功,且应从小剂量用起,从而减少不良反应的发生。
苯扎貝特可能引起肌炎、肌病和橫紋肌溶解癥,儘管髮生率低,但在應用中也應註意肌酶、肝酶、腎功的鑑測和患者癥狀變化,服用前詳細告知患者該藥的不良反應,以便急時髮現;該患者齣現癥狀後急時停用,併查瞭肌酶、肝酶和腎功結閤癥狀證實瞭橫紋肌溶解癥,分析可能的原因除患者腎功輕度降低、貧血等體質原因,首先應瞭解肝腎功,且應從小劑量用起,從而減少不良反應的髮生。
분찰패특가능인기기염、기병화횡문기용해증,진관발생솔저,단재응용중야응주의기매、간매、신공적감측화환자증상변화,복용전상세고지환자해약적불량반응,이편급시발현;해환자출현증상후급시정용,병사료기매、간매화신공결합증상증실료횡문기용해증,분석가능적원인제환자신공경도강저、빈혈등체질원인,수선응료해간신공,차응종소제량용기,종이감소불량반응적발생。
Bzafibrate may cause myositis, myopathy and rhabdomyolysis, although the incidence is low, but in the application should also pay at ention to monitoring and the symptoms change of muscle enzymes, liver enzymes, renal function, before taking the drug adverse reactions in patients with informed, find so that emergency; the patient's symptoms after emergency stop, and check the muscle enzymes, liver enzymes and renal function combined with symptoms that rhabdomyolysis, analysis of possible reasons except for patients with renal slightly decreased, anemia and other physical reasons, should first understand the liver and kidney function, and should be smal dose used, and reduce adverse reaction.