医学信息
醫學信息
의학신식
MEDICAL INFORMATION
2014年
21期
253-253
,共1页
双波长分光光度法%爱索尔感冒片%乙酰水杨酸%含量
雙波長分光光度法%愛索爾感冒片%乙酰水楊痠%含量
쌍파장분광광도법%애색이감모편%을선수양산%함량
Dual wavelength spectrophotometry%Essel cold tablets%Acetylsalicylic acid%Content
目的：建立双波长分光光度法测定爱索尔感冒片中乙酰水杨酸的含量的测定方法。方法样品操作及测定方法同重复性试验,平行操作5批样品,另按照中和滴定法测定,比较两种测定方法测定所得样品的百分标示量。结果双波长法：99.2%,97.9%,98.5%,96.5%,98.2%；中和法：100.8%,98.7%,99.8%,97.1%,99.4%。乙酰水杨酸在255nm的波长处有最大吸收,盐酸吗啉胍在250nm的波长附近为225nm波长的等吸收波长,经过精选,选择250.1nm波长为参比波长,225nm波长为测定波长。乙酰水杨酸乙醇溶液放置3h基本稳定,其他成分的乙醇溶液均稳定。结论采用双波长分光光度法测定爱索尔感冒片中乙酰水杨酸的含量,操作简单,所用试剂方便易得,通过两种试验方法的比较,效果较满意。
目的：建立雙波長分光光度法測定愛索爾感冒片中乙酰水楊痠的含量的測定方法。方法樣品操作及測定方法同重複性試驗,平行操作5批樣品,另按照中和滴定法測定,比較兩種測定方法測定所得樣品的百分標示量。結果雙波長法：99.2%,97.9%,98.5%,96.5%,98.2%；中和法：100.8%,98.7%,99.8%,97.1%,99.4%。乙酰水楊痠在255nm的波長處有最大吸收,鹽痠嗎啉胍在250nm的波長附近為225nm波長的等吸收波長,經過精選,選擇250.1nm波長為參比波長,225nm波長為測定波長。乙酰水楊痠乙醇溶液放置3h基本穩定,其他成分的乙醇溶液均穩定。結論採用雙波長分光光度法測定愛索爾感冒片中乙酰水楊痠的含量,操作簡單,所用試劑方便易得,通過兩種試驗方法的比較,效果較滿意。
목적：건립쌍파장분광광도법측정애색이감모편중을선수양산적함량적측정방법。방법양품조작급측정방법동중복성시험,평행조작5비양품,령안조중화적정법측정,비교량충측정방법측정소득양품적백분표시량。결과쌍파장법：99.2%,97.9%,98.5%,96.5%,98.2%；중화법：100.8%,98.7%,99.8%,97.1%,99.4%。을선수양산재255nm적파장처유최대흡수,염산마람고재250nm적파장부근위225nm파장적등흡수파장,경과정선,선택250.1nm파장위삼비파장,225nm파장위측정파장。을선수양산을순용액방치3h기본은정,기타성분적을순용액균은정。결론채용쌍파장분광광도법측정애색이감모편중을선수양산적함량,조작간단,소용시제방편역득,통과량충시험방법적비교,효과교만의。
Objective To establish a method for determination of dual wavelength determination of acetylsalicylic acid essel cold tablets by spectrophotometry. Methods the sample operation and determination method with repeated experiments, paral el operation of 5 batches of samples, determination of the other in accordance with the neutralization titration method, comparison of two determination methods of the sample percent mark. Results The dual wavelength method: 99.2%, 97.9%, 98.5%, 96.5%, 98.2%; neutralization method: 100.8%, 98.7%, 99.8%, 97.1%, 99.4%. Acetyl salicylic acid has a maximum absorption at 255nm wavelength, Moroxydine Hydrochloride absorption wavelength, 225nm wavelength around 250nm wavelength selected, select the 250.1nm wavelength as the reference wavelength, the wavelength of 225nm as the detection wavelength. Acetyl salicylic acid ethanol solution for 3 hours basical y stable, other components are stable in ethanol solution. Conclusion The operation content, determined by double wavelength acetylsalicylic acid essel cold tablets by spectrophotometry is simple, the reagent is convenient and easy, by comparing the two kinds of test methods, the ef ect is satisfactory.
