中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
22期
151-152,153
,共3页
血管内皮抑素%碱性成纤维细胞生长因子%胃癌
血管內皮抑素%堿性成纖維細胞生長因子%胃癌
혈관내피억소%감성성섬유세포생장인자%위암
Endostatin%Basic fibroblast growth factor%Gastric cancer
目的：分析探讨血管内皮抑素及碱性成纤维细胞生长因子在人胃癌组织中的表达情况。方法：选取来本院就诊的36例胃癌患者，采用免疫组化SP法检测患者胃癌组织中血管内皮抑素和碱性成纤维细胞生长因子的表达水平。结果：发生淋巴结转移和未发生淋巴结转移胃癌患者其胃癌组织中的血管内皮抑素阳性表达率分别为46.7%、81.0%。碱性成纤维细胞生长因子阳性表达率分别为93.3%、61.9%，差异均有统计学意义（P<0.05）。结论：血管内皮抑素及碱性成纤维细胞生长因子是人胃癌组织肿瘤血管的生成过程中的重要调节因子，两者的消长关系可能与胃癌的发生发展等生物学行为相关。
目的：分析探討血管內皮抑素及堿性成纖維細胞生長因子在人胃癌組織中的錶達情況。方法：選取來本院就診的36例胃癌患者，採用免疫組化SP法檢測患者胃癌組織中血管內皮抑素和堿性成纖維細胞生長因子的錶達水平。結果：髮生淋巴結轉移和未髮生淋巴結轉移胃癌患者其胃癌組織中的血管內皮抑素暘性錶達率分彆為46.7%、81.0%。堿性成纖維細胞生長因子暘性錶達率分彆為93.3%、61.9%，差異均有統計學意義（P<0.05）。結論：血管內皮抑素及堿性成纖維細胞生長因子是人胃癌組織腫瘤血管的生成過程中的重要調節因子，兩者的消長關繫可能與胃癌的髮生髮展等生物學行為相關。
목적：분석탐토혈관내피억소급감성성섬유세포생장인자재인위암조직중적표체정황。방법：선취래본원취진적36례위암환자，채용면역조화SP법검측환자위암조직중혈관내피억소화감성성섬유세포생장인자적표체수평。결과：발생림파결전이화미발생림파결전이위암환자기위암조직중적혈관내피억소양성표체솔분별위46.7%、81.0%。감성성섬유세포생장인자양성표체솔분별위93.3%、61.9%，차이균유통계학의의（P<0.05）。결론：혈관내피억소급감성성섬유세포생장인자시인위암조직종류혈관적생성과정중적중요조절인자，량자적소장관계가능여위암적발생발전등생물학행위상관。
To investigate and analyze the expression of somatostatin and alkaline endothelial fibroblast growth factor in human gastric cancer.Method:36 patients with gastric cancer in our hospital were selected,they were detected by immunohistochemical SP method in patients with gastric cancer tissue endostatin and basic fibroblast growth factor expression.Result:The positive expression of endostatin in lymph node metastasis and no lymph node metastasis in gastric cancer patients with gastric carcinoma were 46.7%,81.0%,respectively.Basic fibroblast growth factor expression rates were 93.3%,61.9%,the differences were statistically significant(P<0.05).Conclusion:Somatostatin and alkaline endothelial fibroblast growth factor are the important regulator of tumor angiogenesis in human gastric cancer tissue generation process in the growth,the relationship between them may be related to the occurrence and development of the biological behavior of gastric carcinoma.
