中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
22期
65-66,67
,共3页
牙周治疗%冠心病伴牙周炎%HsCRP%TNF-α%IL-1β
牙週治療%冠心病伴牙週炎%HsCRP%TNF-α%IL-1β
아주치료%관심병반아주염%HsCRP%TNF-α%IL-1β
Periodontal treatment%Coronary heart disease patients with periodontitis%HsCRP%TNF-α%IL-1β
目的：探讨牙周治疗对冠心病伴牙周炎患者血清HsCRP、TNF-α、IL-1β、IL-6水平的影响。方法：选取2012年6月-2013年6月期间本院收治的95例冠心病伴牙周炎患者，均进行牙周综合干预，比较干预前与干预6个月后血清TNF-α，HsCRP、IL-6、IL-1β水平的变化及（牙周炎）附着水平改善的相关性。结果：治疗后患者血清TNF-α，HsCRP、IL-6、IL-1β水平均较治疗前显著降低，差异均有统计学意义（P<0.01）；患者血清TNF-α，HsCRP、IL-6、IL-1β水平与（牙周炎）附着水平呈负相关，差异均有统计学意义（P<0.05）。结论：牙周治疗可有效降低冠心病伴牙周炎患者血清HsCRP、TNF-α、IL-1β、IL-6水平，且患者血清TNF-α、HsCRP、IL-6、IL-1β水平与（牙周炎）附着水平呈负相关，可在一定程度上预测患者牙周炎改善程度。
目的：探討牙週治療對冠心病伴牙週炎患者血清HsCRP、TNF-α、IL-1β、IL-6水平的影響。方法：選取2012年6月-2013年6月期間本院收治的95例冠心病伴牙週炎患者，均進行牙週綜閤榦預，比較榦預前與榦預6箇月後血清TNF-α，HsCRP、IL-6、IL-1β水平的變化及（牙週炎）附著水平改善的相關性。結果：治療後患者血清TNF-α，HsCRP、IL-6、IL-1β水平均較治療前顯著降低，差異均有統計學意義（P<0.01）；患者血清TNF-α，HsCRP、IL-6、IL-1β水平與（牙週炎）附著水平呈負相關，差異均有統計學意義（P<0.05）。結論：牙週治療可有效降低冠心病伴牙週炎患者血清HsCRP、TNF-α、IL-1β、IL-6水平，且患者血清TNF-α、HsCRP、IL-6、IL-1β水平與（牙週炎）附著水平呈負相關，可在一定程度上預測患者牙週炎改善程度。
목적：탐토아주치료대관심병반아주염환자혈청HsCRP、TNF-α、IL-1β、IL-6수평적영향。방법：선취2012년6월-2013년6월기간본원수치적95례관심병반아주염환자，균진행아주종합간예，비교간예전여간예6개월후혈청TNF-α，HsCRP、IL-6、IL-1β수평적변화급（아주염）부착수평개선적상관성。결과：치료후환자혈청TNF-α，HsCRP、IL-6、IL-1β수평균교치료전현저강저，차이균유통계학의의（P<0.01）；환자혈청TNF-α，HsCRP、IL-6、IL-1β수평여（아주염）부착수평정부상관，차이균유통계학의의（P<0.05）。결론：아주치료가유효강저관심병반아주염환자혈청HsCRP、TNF-α、IL-1β、IL-6수평，차환자혈청TNF-α、HsCRP、IL-6、IL-1β수평여（아주염）부착수평정부상관，가재일정정도상예측환자아주염개선정도。
To investigate the effect of periodontal therapy on serum HsCRP,TNF-α,IL-1β,IL-6 level of coronary heart disease patients with periodontitis.Method:95 coronary heart disease patients with periodontitis were selected from June 2012 to June 2013 in our hospital during the period,all patients were given periodontal intervention.The serum TNF-α,HsCRP,IL-6,IL-1βlevel changes and(periodontitis)attachment level improved correlation were compared before the intervention and 6 months after intervention.Result:After treatment, the serum TNF-α,HsCRP,IL-6,IL-1β levels were decreased significantly,the differences were statistically significant(P<0.01),the serum TNF-α,HsCRP,IL-6,IL-1βlevels were negatively correlated with(periodontitis) attachment level,the differences were statistically significant(P<0.05).Conclusion:The periodontal treatment can effectively reduce serum HsCRP,TNF-α,IL-1β,IL-6 level of coronary heart disease patients with periodontitis, and serum TNF-α,HsCRP,IL-6,IL-1βlevels are negatively correlated with(periodontitis)attachment level,and to some extent can predict the degree of improvement in patients with periodontitis.
