中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2014年
23期
25-25,27
,共2页
高危不稳定型心绞痛%替罗非班%维持量%疗效
高危不穩定型心絞痛%替囉非班%維持量%療效
고위불은정형심교통%체라비반%유지량%료효
High risk unstable angina pectoris%Tirofiban%Maintenance dose%Curative effect
目的：分析高危不稳定型心绞痛(UAP)应用不同维持量替罗非班治疗的临床效果与安全性。方法：2013年2月-2014年2月收治 UAP 患者68例，作为研究组，将34例维持量0.05μg/(kg·min)患者作为研究A 组，34例维持量0.1μg/(kg·min)患者作为研究 B 组，另选35例同期未应用替罗非班治疗的 UAP 患者作对照组，记录并分析相关数据。结果：研究A、B两组治疗后的ST段下移幅度比对照组小，研究B组的轻微出血率比其他两组高，对照组的再发心绞痛与急性心肌梗死发生率比研究 A、B 两组高，差异有统计学意义(P＜0.05)。结论：UAP 应用维持量0.05μg/(kg·min)替罗非班治疗，临床效果显著且安全性高。
目的：分析高危不穩定型心絞痛(UAP)應用不同維持量替囉非班治療的臨床效果與安全性。方法：2013年2月-2014年2月收治 UAP 患者68例，作為研究組，將34例維持量0.05μg/(kg·min)患者作為研究A 組，34例維持量0.1μg/(kg·min)患者作為研究 B 組，另選35例同期未應用替囉非班治療的 UAP 患者作對照組，記錄併分析相關數據。結果：研究A、B兩組治療後的ST段下移幅度比對照組小，研究B組的輕微齣血率比其他兩組高，對照組的再髮心絞痛與急性心肌梗死髮生率比研究 A、B 兩組高，差異有統計學意義(P＜0.05)。結論：UAP 應用維持量0.05μg/(kg·min)替囉非班治療，臨床效果顯著且安全性高。
목적：분석고위불은정형심교통(UAP)응용불동유지량체라비반치료적림상효과여안전성。방법：2013년2월-2014년2월수치 UAP 환자68례，작위연구조，장34례유지량0.05μg/(kg·min)환자작위연구A 조，34례유지량0.1μg/(kg·min)환자작위연구 B 조，령선35례동기미응용체라비반치료적 UAP 환자작대조조，기록병분석상관수거。결과：연구A、B량조치료후적ST단하이폭도비대조조소，연구B조적경미출혈솔비기타량조고，대조조적재발심교통여급성심기경사발생솔비연구 A、B 량조고，차이유통계학의의(P＜0.05)。결론：UAP 응용유지량0.05μg/(kg·min)체라비반치료，림상효과현저차안전성고。
To analyze the clinical effect and safety of different maintenance dose of tirofiban in the treatment of high risk unstable angina pectoris(UAP).Methods:68 cases with UAP were selected from February 2013 to February 2014.They were as the research group.34 cases with the maintenance dose of 0.05 μg/(kg·min) were as the research A group.34 cases with the maintenance dose of 0.1 μg/(kg·min) were as the research B group.Another 35 cases with UAP without application of tirofiban were as the control group.The relevant data were recorded and analyzed.Results:After treatment,ST segment down ranges of the research A group and B group were smaller than that of the control group.The slight bleeding rate of research B group was higher than that of other two groups.The incidence rates of recurrence angina and acute myocardial infarction were higher than that of the research A group and B group.The difference was statistically significant(P<0.05).Conclusion:The maintenance dose of 0.05 μg/(kg·min) tirofiban is applied in treating UAP.It has remarkable clinical effect and high safety.
