中国药业
中國藥業
중국약업
CHINA PHARMACEUTICALS
2014年
14期
56-57
,共2页
双氯芬酸二乙胺乳胶剂%高效液相色谱法%含量测定
雙氯芬痠二乙胺乳膠劑%高效液相色譜法%含量測定
쌍록분산이을알유효제%고효액상색보법%함량측정
Diclofenac Diethylamine Emulgel%HPLC%content determination
目的：建立测定双氯芬酸二乙胺乳胶剂含量的高效液相色谱法。方法以甲醇-4%冰醋酸（70：30）为流动相，色谱柱为 CNW C18柱（150 mm ×4.6 mm，5μm），检测波长为276 nm。结果双氯芬酸钠质量浓度在51.600~1290.0μg / mL 范围内与峰面积呈良好线性关系，双氯芬酸钠的平均回收率为98.53%，RSD 为0.71%。结论该方法简单、灵敏度高，可用于双氯芬酸二乙胺乳胶剂的含量测定。
目的：建立測定雙氯芬痠二乙胺乳膠劑含量的高效液相色譜法。方法以甲醇-4%冰醋痠（70：30）為流動相，色譜柱為 CNW C18柱（150 mm ×4.6 mm，5μm），檢測波長為276 nm。結果雙氯芬痠鈉質量濃度在51.600~1290.0μg / mL 範圍內與峰麵積呈良好線性關繫，雙氯芬痠鈉的平均迴收率為98.53%，RSD 為0.71%。結論該方法簡單、靈敏度高，可用于雙氯芬痠二乙胺乳膠劑的含量測定。
목적：건립측정쌍록분산이을알유효제함량적고효액상색보법。방법이갑순-4%빙작산（70：30）위류동상，색보주위 CNW C18주（150 mm ×4.6 mm，5μm），검측파장위276 nm。결과쌍록분산납질량농도재51.600~1290.0μg / mL 범위내여봉면적정량호선성관계，쌍록분산납적평균회수솔위98.53%，RSD 위0.71%。결론해방법간단、령민도고，가용우쌍록분산이을알유효제적함량측정。
Objective To establish a HPLC method for the content determination of Diclofenac Diethylamine Emulgel. Methods The separation was performed on the CNW C18 column(150 mm × 4. 6 mm,5 μm). The mobile phase was methanol - 4% glacial acetic acid solution(70 : 30). The UV detection wavelength was set at 276 nm. Results The mass concentration of diclofenac diethylamine in the range of 51. 600 - 1 290. 0 μg / mL had a good linear relation with the peak area,the average recovery rate of diclofenac diethylamine was 98. 53% ,RSD = 0. 71% . Conclusion This method is simple,highly sensitive and can be used for the content determination of Di-clofenac Diethylamine Emulgel.
